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SiliCycle offers a wide range of scavengers to simplify you purification. Scavengers are functionalized silica designed to react and bind excess reagents and/or by products. The process for using scavengers is outlined below in figure 1.
In the case of batch processing the scavenger is added to the reaction mixture after completion. The process relies on chemically driven reactions where the excess reagents and reaction byproducts react with and bind to the scavenger. The solution which now only contains product is separated from the resin bound impurities by filtration.
For flow through processing the scavenger is packed into a column (SPE, HPLC, etc) and the reaction mixture is passed through or recirculated through the column until scavenging is complete. Recirculating solution through the packed column is normally only applicable on large scale, pilot plant or higher.
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