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Manufacturers > SiliCycle > Silica Bound Scavengers & Reagents > Scavengers > Metal |
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Metal |
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Removing residual transition metal post reaction is a major issue for many chemists, particularly process chemists in the pharmaceutical industry, where the toxic nature of transition metals means their concentration has to be reduced to the single digit ppm level for the material to be used in vivo and clinical work. SiliCycle has a wide range of scavengers that can remove a variety of transition metals (Table 1).
When selecting a metal scavenger for your reaction every component in the reaction mixture must be considered; the solvent and ligand are key factors but the product, residual reagents, and by-products can all affect scavenger performance. Please view our case study on Pd removal for more information. |
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Metal Scavenger Selection Guide |
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| Scavenger |
Pd(II) |
Pd(0) |
Sn |
Zn |
Pb |
Ni(II) |
Ni(O) |
Pt |
Cu |
Cd |
Co |
Rh |
Ru |
Ag |
Hg |
Fe(III) |
| SiliaMet-Amine |
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| SiliaMet-Diamine |
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| SiliaMet- Triamine |
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| SiliaMet-Thiol |
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| SiliaMet-EDAB |
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| SiliaMet-TAAcOH |
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| SiliaMet-TAAcONa |
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| SiliaMet-Thiourea |
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| SiliaMet-DMT |
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| SiliaMet-Imidazole |
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| SiliaMet-TBD |
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| = Preferred Product |
= Scavenges |
= Reported in the literature or by customers |
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| Scavenger |
Pd(AcO)2 |
Pd2(C3H5)2Cl2 |
Pd(PPh3)4 |
Pd2(dba)3 |
Ni(AcO)2 |
| SiliaMet-Thiol |
0.07 |
0.04 |
150 |
20 |
-- |
| SiliaMet-Thiourea |
0.8 |
1.3 |
95 |
50 |
-- |
| SiliaMet-TAAcOH |
0.06 |
0.25 |
1.4 |
50 |
60 |
| SiliaMet-TAAcONa |
42 |
-- |
144 |
-- |
10 |
| SiliaMet- Triamine |
0.3 |
1.3 |
220 |
280 |
-- |
| Scavenging of different metal complexes at RT THF. Starting concentration 1000ppm |
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| Part number |
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Name |
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Description |
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Picture |
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Loading |
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R48030B-25G |
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SiliaMet-Triamine |
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Metal Scavenger: Pb, Ru, Co, Hg, and Pd |
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1.3 mmol / g |
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| SiliaMet-Triamine other sizes |
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R49030B-25G |
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SiliaMet-Diamine |
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Metal Scavenger: Zn, Ni(II), Pb, Cd, Hg |
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1.4 mmol / g |
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| SiliaMet-Diamine other sizes |
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R51030B-25G |
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SiliaMet-Thiol |
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Metal Scavenger: Pd, Pt, Cu, Ag, and Pb |
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1.2 mmol / g |
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| SiliaMet-Thiol other sizes |
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R69030B-25G |
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SiliaMet-TAAcOH |
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Acid and Metal Scavenger |
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0.5 mmol / g |
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| SiliaMet-TAAcOH other sizes |
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*NEW*
R69230B-25G |
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SiliaMet-TAAcONa |
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Metal Scavenger: Pd(II), Ni(II), Cu(II) |
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0.5 mmol / g |
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| SiliaMet-TAAcONa other sizes |
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R69530B-25G |
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SiliaMet-Thiourea |
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Metal Scavenger: Pd, Pt, Rh, Ru, Hg |
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1.1 mmol / g |
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| SiliaMet-Thiourea other sizes |
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*NEW*
R79030B-25G |
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SiliaMet--DMT |
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Metal Scavenger: Pd, Pt, Rh, Ru, Ni |
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>0.5 mmol / g |
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| SiliaMet-DMT other sizes |
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*NEW*
R79230B-25G |
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SiliaMet-Imidazole |
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Metal Scavenger: Cd, Co, Cu, Fe, Ni, Pd, Rh |
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>0.9 mmol / g |
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| SiliaMet-Imidazole other sizes |
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