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ZORBAX Eclipse XDB HPLC Columns

ZORBAX Eclipse XDB Structure  

The Agilent ZORBAX Eclipse XDB columns – C18, C8, Phenyl and CN – provide four bonded phase choices for method development optimization.
These columns provide good peak shape over a wide pH range (2-9) for additional method development flexibility with one family of columns. Eclipse XDB columns can be used for method development at low pH (2-3) and the same column can be used for method development in the mid pH (6-8) region. In the mid pH region residual silanols are more active and tailing interactions are more likely.
To overcome these interactions, Eclipse XDB columns are eXtra Densely Bonded and double endcapped through a proprietary process to cover as many active silanols as possible. The result is superior peak shape of basic compounds from pH 2-9.

  • Four selectivity choices for method development optimization
  • Good peak shape for basic, acidic and neutral compounds
  • High performance over a wide pH range – pH 2-9
  • Particle sizes from 1.8 μm to 7 μm
  • Long lifetime with extra dense bonding and double endcapping

Eclipse XDB columns are available in the following particle sizes:

     
     

ZORBAX Eclipse XDB Analytical HPLC Columns

This is the particle size for almost all standard analytical HPLC assays. For full details of the range of analytical columns available please see below.
     
ZORBAX Eclipse XDB Columns Show Good Peak Shape
     
Description
5µm columns
Size (mm)
Eclipse
XDB C18
USP L1
Eclipse
XDB C8
USP L7
Eclipse
XDB Phenyl
USP L11
Eclipse
XDB CN
USP L10
           
Semi-Preparative 9.4 x 250
990967-202
990967-206
   
Analytical 4.6 x 250
990967-902
990967-906
990967-912
990967-905
Analytical 4.6 x 150
993967-902
993967-906
993967-912
993967-905
Analytical 4.6 x 50
946975-902
946975-906
   
Solvent Saver 3.0 x 250
990967-302
990967-306
990967-312
990967-305
Solvent Saver 3.0 x 150
993967-302
993967-306
993967-312
993967-305
Narrow Bore 2.1 x 150
993700-902
993700-906
993700-912
993700-905
Narrow Bore 2.1 x 50
960967-902
960967-906
960967-912
960967-905
MicroBore Guard Cartridges, 3/pk 1.0 x 17
5185-5921
5185-5921
   
Guard Cartridges, 4/pk 4.6 x 12.5
820950-925
820950-926
820950-927
820950-935
Guard Cartridges, 4/pk 2.1 x 12.5
821125-926
821125-926
821125-926
821125-935
PrepHT Cartridge 21.2 x 150
970150-902
970150-906
   
PrepHT Cartridge 21.2 x 100
970100-902
970100-906
   
PrepHT Cartridge 21.2 x 50
970050-902
970050-906
   
PrepHT Guard Cartridge 17 x 7.5
820212-925
820212-926
   
Capillary 0.5 x 250
5064-8286
     
Capillary 0.5 x 150
5064-8287
     
Capillary 0.3 x 250
5064-8269
     
Capillary 0.3 x 150
5064-8291
     
Capillary 0.5 x 35
5064-8296
     
Capillary 0.3 x 35
5064-8297
     
     

ZORBAX Eclipse XDB Rapid Resolution HPLC Columns

  • Reduce analysis time and solvent usage and increase sample throughput
  • High efficiency in short and ultra-short column lengths
  • Available in analytical (4.6 mm) and narrow-bore (2.1 mm) ID
  • Comparable lifetime to 5 μm columns
     
Agilent ZORBAX Rapid Resolution columns, with a 3.5 μm particle size, reduce analysis time and increase sample throughput for any application when compared to 5 μm columns. Rapid Resolution columns are available from 15-150 mm, in 1-4.6 mm IDs, so the best configurations are available for high throughput, LC/MS, combinatorial chemistry and rapid analytical applications. Rapid Resolution 3.5 μm particles have superior mechanical strength, so every column has an extremely stable packed bed and provides a comparable lifetime to 5 μm columns.
     
ZORBAX Eclipse XDB Rapid Resolution Separation of Drugs
     
Description

3.5µm Columns
Size (mm) Eclipse
XDB C18
USP L1
Eclipse
XDB C8
USP L7
Eclipse
XDB Phenyl
USP L11
Eclipse
XDB CN
USP L10
           
Rapid Resolution 4.6 x 150
963967-902
963967-906
963967-912
963967-905
Rapid Resolution 4.6 x 100
961967-902
961967-906
 
961967-905
Rapid Resolution 4.6 x 75
966967-902
966967-906
966967-912
966967-905
Rapid Resolution 4.6 x 50
935967-902
935967-906
935967-912
 
Solvent Saver Plus 3.0 x 150
963954-302
963954-306
963954-312
963954-305
Solvent Saver Plus 3.0 x 100
961967-302
961967-306
961967-312
 
Solvent Saver Plus 3.0 x 75
966954-302
     
Narrow Bore RR 2.1 x 150
930990-902
930990-906
   
Narrow Bore RR 2.1 x 100
961753-902
961753-906
 
961753-905
Narrow Bore RR 2.1 x 75
966735-902
     
Narrow Bore RR 2.1 x 50
971700-902
971700-906
   
MicroBore RR 1.0 x 150
963600-902
963600-906
   
MicroBore RR 1.0 x 50
965600-902
965600-906
   
MicroBore RR 1.0 x 30
961600-902
961600-906
   
Rapid Resolution Cartridge 4.6 x 30
933975-902
933975-906
   
Rapid Resolution Cartridge, 3/pk 4.6 x 30
933975-932
933975-936
   
Rapid Resolution Cartridge 4.6 x 15
931975-902
931975-906
   
Rapid Resolution Cartridge, 3/pk 4.6 x 15
931975-932
931975-936
   
Rapid Resolution Cartridge 2.1 x 30
973700-902
973700-906
   
Rapid Resolution Cartridge, 3/pk 2.1 x 30
973700-932
973700-936
   
Rapid Resolution Cartridge 2.1 x 15
975700-902
975700-906
   
Rapid Resolution Cartridge, 3/pk 2.1 x 15
975700-932
975700-936
   
Capillary RR 0.5 x 150
5064-8288
     
Capillary RR 0.5 x 35
5064-8298
     
Capillary RR 0.3 x 150
5064-8271
     
     

ZORBAX Eclipse XDB Rapid Resolution High Throughput HPLC Columns

  • New high pressure (600 bar) columns for ultra high speed or maximum resolution analyses with Rapid Resolution HT columns packed with totally porous, 1.8 μm packings
  • Carefully engineered particles deliver maximum resolution at 25% less pressure than other sub 2-micron materials
  • Reduce analysis time by up to 95%
  • Develop HPLC methods more quickly
  • Securely transfer conventional methods with over 80 RRHT column choices
  • Analyze complex samples on shorter columns faster and maximize peak capacity
  • Perform faster analyses and use less solvent
  • Short (50 mm long and less) column can be used on some conventional LCs
     
ZORBAX Eclipse XDB RRHT Separation of Flavours
     
ZORBAX Rapid Resolution HT (1.8 μm) columns use a totally porous, 1.8 μm particle to provide maximum resolution in fast, ultra-fast and high resolution analyses. You can reduce analysis time by up to 95% in comparison to 250 mm length columns. The small particle size provides double the efficiency of a 3.5 μm column in the same column length providing the highest efficiency and resolution possible. This permits the analysis of complex samples on shorter column with the highest resolution and peak capacity. The 1.8 μm Rapid Resolution HT columns take high-speed, high-resolution HPLC to a new level. The 600 bar columns can be used with the new Agilent 1200 Rapid Resolution LC up to this high pressure limit. In addition, the shorter columns can be used on many other LC's, including the Agilent 1100 by using the RRHT-1100 conversion kits to maximize performance.
     
Description

1.8µm columns
Size (mm) Eclipse
XDB C18
USP L1
Eclipse
XDB C8
USP L7
       
Rapid Resolution HT, 600 bar 4.6 x 100
928975-902
928975-906
Rapid Resolution HT, 600 bar 4.6 x 50
927975-902
927975-906
Rapid Resolution HT, 600 bar 4.6 x 30
924975-902
924975-906
Rapid Resolution HT, 600 bar 4.6 x 20
926975-902
926975-906
Solvent Saver HT, 600 bar 3.0 x 100
928975-302
928975-306
Solvent Saver HT, 600 bar 3.0 x 50
927975-302
927975-306
Solvent Saver HT, 600 bar 3.0 x 30
924975-302
924975-306
Solvent Saver HT, 600 bar 3.0 x 20
926975-302
926975-306
Narrow Bore RRHT, 600 bar 2.1 x 100
928700-902
928700-906
Narrow Bore RRHT, 600 bar 2.1 x 50
927700-902
927700-906
Narrow Bore RRHT, 600 bar 2.1 x 30
924700-902
924700-906
Narrow Bore RRHT, 600 bar 2.1 x 20
926700-902
926700-906
Rapid Resolution HT 4.6 x 50
922975-902
922975-906
Rapid Resolution HT, 3/pk 4.6 x 50
922975-932
 
Narrow Bore RRHT 2.1 x 50
922700-902
 
Narrow Bore RRHT, 3/pk 2.1 x 50
922700-932
 
Rapid Resolution HT Cartridge 4.6 x 50
925975-902
 
Rapid Resolution HT Cartridge, 3/pk 4.6 x 50
925975-932
 
Rapid Resolution HT Cartridge 4.6 x 30
923975-902
 
Rapid Resolution HT Cartridge, 3/pk 4.6 x 30
923975-932
 
Rapid Resolution HT Cartridge 4.6 x 15
921975-902
 
Rapid Resolution HT Cartridge, 3/pk 4.6 x 15
921975-932
 
Rapid Resolution HT Cartridge 2.1 x 50
925700-902
 
Rapid Resolution HT Cartridge, 3/pk 2.1 x 50
925700-932
 
Rapid Resolution HT Cartridge 2.1 x 30
923700-902
 
Rapid Resolution HT Cartridge, 3/pk 2.1 x 30
923700-932
 
Rapid Resolution HT Cartridge 2.1 x 15
921700-902
 
Rapid Resolution HT Cartridge, 3/pk 2.1 x 15
921700-932
 
     
ZORBAX Eclipse XDB Rapid Resolution High Definition HPLC Columns
 
Description Size (mm) 
ParticleSize (μm) 
Part Number
Zorbax Eclipse XDB C18 1.8µm
Rapid Resolution HD, 1200 bar 3.0 x 150
1.8
981759-302
Rapid Resolution HD, 1200 bar 3.0 x 100
1.8
981758-302
Rapid Resolution HD, 1200 bar 3.0 x 50
1.8
981757-302
Rapid Resolution HD, 1200 bar 2.1 x 150
1.8
981759-902
Rapid Resolution HD, 1200 bar 2.1 x 100
1.8
981758-902
Rapid Resolution HD, 1200 bar 2.1 x 50
1.8
981757-902
 


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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