YMC-Pack Amino is based on a monomeric bonding of a primary propylamine functionality to YMC’s spherical, ultra pure, high surface area silica with a mean pore diameter of 12 nm. The amine functionality provides retention and allows the separation of polar compounds under aggressive normal phase elution conditions, e.g. the analysis of mono- and polysaccharides using acetonitrile/water eluents. (Since YMC-Gel Amino packings operate under normal phase / HILIC elution conditions, water, which is more polar than acetonitrile, is the stronger solvent.) YMC-Pack Amino can also be used for the separation of isomers of tocopherols and other organic soluble compounds such as paraffins, olefins and aromatics under conventional normal phase conditions.
In aqueous, low pH buffers the amino phase becomes a weak anion exchanger capable of separating negatively charged molecules.