| YMC-Pack Pro C18 |
YMC-Pack Pro C18 is based on an ultra pure silica support which is used for the whole ProFamily. Due to proprietry andcapping this column is perfectly suitable for the separation of acidic and basic molecules. The inertness of the silica makes it an excellent choice for the analysis of drugs and their metabolites as well as compounds that are susceptible to polar interactions with residual silanol groups and metals.
Extremely basic substances are selected to prove the performance of YMC-Pack Pro C18 with regards to their separation and peak performance which cannot be acheived with classical materials. |
| Separation of extremely basic compounds |
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Tricyclic antidepressants
Column dimensions: 4.6 x 150 mm, 5 µm
Eluent: 20 mM potassium phosphate (pH 6.9):methanol (25:75)
Flow rate: 1.0 mL/min
Temperature: 37°C
Detection: UV at 254 nm |
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- Specifically designed for research and development in the pharmaceutical and biotechnology industries
- Extremely narrow specifications
- High lot-to-lot reproducibility
- High column-to-column reproducibility
- Ideal for basic, acidic and polar compounds
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| Specifications |
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YMC-Pack Pro C18 |
| Particle size (µm) |
2, 3, 5 |
| Pore size (nm) |
12 |
| Surface area (m2/g) |
330 |
| Carbon content (%) |
16 |
| Recommended pH range |
2.0-8.0 |
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| Reproducibility |
High lot-to-lot reproducibility is the essential basis for high performance HPLC columns.
High column performance can only be achieved if a column is well packed to give continuously high numbers of theoretical plates and therefore good asymmetry factors. The figure below clearly demonstrates YMC's high level of reproducible quality from column to column. |
| Column-to-column comparison for consecutive packed columns |
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Column dimensions: 4.6 x 150 mm, 5 µm
Mobile phase: 60:40 acetonitrile:water
Flow rate: 1.0 mL/min
Detection: UV at 270 nm, 0.32 AUFS
Temperature: 25 ºC |
| Plate count and asymmetry were calculated for butyl benzoate. |
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| Column care |
YMC Pack Pro C18 is stable towards hydrolysis between pH 2-8. Remove acid and buffer salts before storage. Store the column in 70:30 methanol:water.
For detailed information please refer to the “Column Care and Use Instructions” which are shipped with each analytical column. |
| Ordering Information |
3 µm
12 nm |
Column Length (mm) |
| Column I.D. (mm) |
30(WT)/
33(QT) |
50 |
100 |
150 |
250 |
Guards
(10 mm) 5/pk |
| 2.1 |
AS12S03-H3Q1QT |
AS12S03-05Q1QT |
AS12S03-10Q1QT |
AS12S03-15Q1QT |
AS12S03-25Q1QT |
AS12S03-01Q1GC |
| 3.0 |
AS12S03-H303QT |
AS12S03-0503QT |
AS12S03-1003QT |
AS12S03-1503QT |
AS12S03-2503QT |
AS12S03-0103GC |
| 4.0 |
AS12S03-H304QT |
AS12S03-0504QT |
AS12S03-1004QT |
AS12S03-1504QT |
AS12S03-2504QT |
AS12S03-0104GC |
| 4.6 |
AS12S03-0346WT |
AS12S03-0546WT |
AS12S03-1046WT |
AS12S03-1546WT |
AS12S03-2546WT |
AS12S03-0104GC |
5 µm
12 nm |
Column Length (mm) |
| Column I.D. (mm) |
30(WT)/
33(QT) |
50 |
100 |
150 |
250 |
Guards
(10 mm) 5/pk |
| 2.1 |
AS12S05-H3Q1QT |
AS12S05-05Q1QT |
AS12S05-10Q1QT |
AS12S05-15Q1QT |
AS12S05-25Q1QT |
AS12S05-01Q1GC |
| 3.0 |
AS12S05-H303QT |
AS12S05-0503QT |
AS12S05-1003QT |
AS12S53-1503QT |
AS12S05-2503QT |
AS12S05-0103GC |
| 4.0 |
AS12S05-H304QT |
AS12S05-0504QT |
AS12S05-1004QT |
AS12S05-1504QT |
AS12S05-2504QT |
AS12S05-0104GC |
| 4.6 |
AS12S05-0346WT |
AS12S05-0546WT |
AS12S05-1046WT |
AS12S05-1546WT |
AS12S05-2546WT |
AS12S05-0104GC |
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** Guard cartridge holder required is part number XPGCH-Q1
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