Fundamental ICP-MS Training Course
An introduction to the fundamental concepts and principles associated with ICP-MS
Attendees will gain useful insight into the operating principles of ICP-MS instruments.
This comprehensive, one-day course is designed to increase expertise and optimise results for all users of ICP-MS.
Understanding sample introduction and the optimisation of instrument performance are key subjects within this one-day course. Interactive training sessions and tutorial exercises are used to reinforce key learning points.
- How the ICP source differs to other MS techniques, offering a complementary view of the chemicals being analysed
- Why ICP-MS is particularly suitable for a wide range of applications including isotope ratio studies.
- How ICP-MS can be used for the analysis of ultra-trace metal elements (0.0005-100ppb)
- Application of ICP-MS to non-metallic elements (e.g. S, P)
Introduction to IPC-MS
- What can ICP-MS do?
- Schematic design
Inductively Coupled Plasmas
- Plasma formation
- Load coils
- Plasma configuration
Liquid Sample Introduction
- The cross-flow nebuliser
- The concentric nebuliser
- The Babington nebuliser
- Spray chambers
The Mass Spectrometer
- The vacuum and interface systems
- Ion lenses
- Photon stops
- Off-Axis deflection
- Space Charge effect
- Quadrupole theory
- Alternative Analysers
- Tuning and calibration/Plasma parameters
- Continuous Dynode Electron Multiplier
Interferences and Removal
- Polyatomic and Isobaric interferences
- Double Charge and Oxide species
- Plasma / Matrix effects
- Collision / Reaction Cells
- Kinetic Energy Discrimination
- External / Internal Standards
- Isotope Dilution
- Standard Addition
This course is tailored towards either the experienced user who is looking for a refresher course or new users who are looking for an introduction to the analytical technique.
Background knowledge of ICP-OES or mass spectrometry may be useful but not necessary, as all the essentials are covered in the course. Previous experience using ICP-MS equipment can be beneficial.
HPLC Method Development
Calibration and Quantitation