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GC Headspace

Half Day

Learn all you need to know about this elegant yet complex sample preparation/introduction of GC samples

This half day course provides a comprehensive coverage of the most common approaches associated with static headspace methods used in GC.

We look at the foundation principles of the technique, then move to the practical aspects of operation, instrumentation troubleshooting and optimisation/development of conditions.

●      General concepts and benefits

●      Most critical parameters for HS sampling

●      GC requirements and specifics of HS instrumentation

●      Guidelines to method development

●      Quantitative approaches to HS analysis


  • Headspace principles
  • Boyle's Law
  • Dalton's Law of partial pressures
  • Matrix effects
  • Instrument Design

Vial pressurisation methods

  • Pressure Testing
  • Sampling valve and carrier flow
  • Loop filling
  • Transfer line
  • Common problems and troubleshooting

Headspace Vials

  • Vial types
  • Closure types
  • Closure quality and pressure integrity
  • Vial size

Internal Standards

  • Selecting an internal standard
  • Evaluating and optimising internal standard performance

GC Requirements

  • Inlet types
  • Carrier requirements
  • Liner types
  • Oven conditions and focusing

Development and Optimisation of Conditions

  • Solvent selection
  • Oven conditions
  • Fill volume
  • Use of salt
  • Sampling conditions

Total Headspace Extraction

Multiple Headspace Extraction

Standard Addition method

This course is relevant to anyone using static headspace sampling for GC analysis. It is applicable to most instrument designs.

Good knowledge of chromatography and associated data.

Operating & Understanding GC

GC Troubleshooting

GC Method Development


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