SiELC Primesep P HPLC Columns

SiELC Primesep P is a mixed-mode HPLC column that embeds both aromatic and acidic ion-pairing groups on a short carbon chain. It provides improved retention of basic compounds through a cation-exchange mechanism, differentiates aromatic compounds based on the variations in pi-pi interaction, and retains neutral compounds using a reversed phase mechanism. Depending on analyte properties, one, two, or all three interactions can be applied to the separation. Primesep P is particularly useful for the separation of structural isomers of aromatic compounds and the degree of pi-pi interaction can be adjusted by varying the amount of acetonitrile in the mobile phase.

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Part Number	Short Description	Phase	Particle Size	ID	Length	Pore Size	Type	Price
P-05.250.0510	Primesep P Column 0.5 x 250mm 5um 100A	Primesep P	5 um	0.5 mm	250 mm	100 A	Column	£1,409.00
P-05.150.0510	Primesep P Column 0.5 x 150mm 5um 100A	Primesep P	5 um	0.5 mm	150 mm	100 A	Column	£1,372.24
P-46.250.0510	Primesep P Column 4.6 x 250mm 5um 100A	Primesep P	5 um	4.6 mm	250 mm	100 A	Column	£1,280.36
P-05.100.0510	Primesep P Column 0.5 x 100mm 5um 100A	Primesep P	5 um	0.5 mm	100 mm	100 A	Column	£1,372.24
P-46.150.0510	Primesep P Column 4.6 x 150mm 5um 100A	Primesep P	5 um	4.6 mm	150 mm	100 A	Column	£1,170.08
P-32.250.0510	Primesep P Column 3.2 x 250mm 5um 100A	Primesep P	5 um	3.2 mm	250 mm	100 A	Column	£1,237.47
P-10.250.0510	Primesep P Column 1 x 250mm 5um 100A	Primesep P	5 um	1.0 mm	250 mm	100 A	Column	£1,200.72
P-21.250.0510	Primesep P Column 2.1 x 250mm 5um 100A	Primesep P	5 um	2.1 mm	250 mm	100 A	Column	£1,200.72
P-46.100.0510	Primesep P Column 4.6 x 100mm 5um 100A	Primesep P	5 um	4.6 mm	100 mm	100 A	Column	£1,133.34
P-32.150.0510	Primesep P Column 3.2 x 150mm 5um 100A	Primesep P	5 um	3.2 mm	150 mm	100 A	Column	£1,176.20
P-10.150.0510	Primesep P Column 1 x 150mm 5um 100A	Primesep P	5 um	1.0 mm	150 mm	100 A	Column	£1,151.71
P-21.150.0510	Primesep P Column 2.1 x 150mm 5um 100A	Primesep P	5 um	2.1 mm	150 mm	100 A	Column	£1,151.71
P-32.100.0510	Primesep P Column 3.2 x 100mm 5um 100A	Primesep P	5 um	3.2 mm	100 mm	100 A	Column	£1,133.34
P-10.100.0510	Primesep P Column 1 x 100mm 5um 100A	Primesep P	5 um	1.0 mm	100 mm	100 A	Column	£1,133.34
P-21.100.0510	Primesep P Column 2.1 x 100mm 5um 100A	Primesep P	5 um	2.1 mm	100 mm	100 A	Column	£1,133.34
P-10.050.0510	Primesep P Column 1 x 50mm 5um 100A	Primesep P	5 um	1.0 mm	50 mm	100 A	Column	£1,096.57
P-21.050.0510	Primesep P Column 2.1 x 50mm 5um 100A	Primesep P	5 um	2.1 mm	50 mm	100 A	Column	£1,096.57
P-32.050.0510	Primesep P Column 3.2 x 50mm 5um 100A	Primesep P	5 um	3.2 mm	50 mm	100 A	Column	£1,096.57
P-46.050.0510	Primesep P Column 4.6 x 50mm 5um 100A	Primesep P	5 um	4.6 mm	50 mm	100 A	Column	£1,029.19
P-10.025.0510	Primesep P Column 1 x 25mm 5um 100A	Primesep P	5 um	1.0 mm	25 mm	100 A	Column	£980.18
P-21.025.0510	Primesep P Column 2.1 x 25mm 5um 100A	Primesep P	5 um	2.1 mm	25 mm	100 A	Column	£980.18
P-32.025.0510	Primesep P Column 3.2 x 25mm 5um 100A	Primesep P	5 um	3.2 mm	25 mm	100 A	Column	£980.18
P-10.010.0510	Primesep P Column 1 x 10mm 5um 100A	Primesep P	5 um	1.0 mm	10 mm	100 A	Column	£888.29
P-21.010.0510	Primesep P Column 2.1 x 10mm 5um 100A	Primesep P	5 um	2.1 mm	10 mm	100 A	Column	£888.29
P-32.010.0510	Primesep P Column 3.2 x 10mm 5um 100A	Primesep P	5 um	3.2 mm	10 mm	100 A	Column	£888.29
P-46.010.0510	Primesep P Column 4.6 x 10mm 5um 100A	Primesep P	5 um	4.6 mm	10 mm	100 A	Column	£790.27
P-10.G.0510	Primesep P Guard Column 1 x 10mm 5um 100A, 2pk	Primesep P	5 um	1.0 mm	10 mm	100 A	Guard	£416.57
P-21.G.0510	Primesep P Guard Column 2.1 x 10mm 5um 100A, 2pk	Primesep P	5 um	2.1 mm	10 mm	100 A	Guard	£416.57
P-32.G.0510	Primesep P Guard Column 3.2 x 10mm 5um 100A, 2pk	Primesep P	5 um	3.2 mm	10 mm	100 A	Guard	£416.57
P-46.G.0510	Primesep P Guard Column 4.6 x 10mm 5um 100A, 2pk	Primesep P	5 um	4.6 mm	10 mm	100 A	Guard	£416.57
P-100.050.0510	Primesep P Column 10 x 50mm 5um 100A	Primesep P	5 um	10.0 mm	50 mm	100 A	Column	£2,839.72
P-100.100.0510	Primesep P Column 10 x 100mm 5um 100A	Primesep P	5 um	10.0 mm	100 mm	100 A	Column	£3,394.20
P-100.150.0510	Primesep P Column 10 x 150mm 5um 100A	Primesep P	5 um	10.0 mm	150 mm	100 A	Column	£3,965.51
P-100.250.0510	Primesep P Column 10 x 250mm 5um 100A	Primesep P	5 um	10.0 mm	250 mm	100 A	Column	£5,192.15
P-220.050.0510	Primesep P Column 22 x 50mm 5um 100A	Primesep P	5 um	22.0 mm	50 mm	100 A	Column	£5,091.33
P-220.100.0510	Primesep P Column 22 x 100mm 5um 100A	Primesep P	5 um	22.0 mm	100 mm	100 A	Column	£5,847.47
P-220.150.0510	Primesep P Column 22 x 150mm 5um 100A	Primesep P	5 um	22.0 mm	150 mm	100 A	Column	£7,275.73
P-220.250.0510	Primesep P Column 22 x 250mm 5um 100A	Primesep P	5 um	22.0 mm	250 mm	100 A	Column	£9,157.67

Features

Primesep P is a mixed-mode HPLC column that embeds both aromatic and acidic ion-pairing groups on a short carbon chain
Three interactions on one column - reversed phase, pi-pi, and strong cation exchange
Improved retention of basic compounds through a cation-exchange mechanism
Distinguishes aromatic compounds based on the variations in pi-pi interaction
Retains neutral compounds using a reversed phase mechanism
Choose for separation of structural isomers of aromatic compounds
Offers mobile phase compatibility with LC-MS
Scalable from capillary to prep
Guard columns connect directly to columns and do not require any additional holders

Specifications

	Primesep P
Mode	Mixed-Mode
Phase Type	Embedded aromatic and acidic ion-pairing groups on a short carbon chain
Particle Type	Fully Porous
Particle Size	5 µm
Pore Size	100 Å
Temperature Range	0 - 50°C
pH Limit	1.5 - 7.0
Recommended pH Operating Range	2.0 - 6.5
Pressure Limit	345 bar

Literature

SiELC Primesep Brochure (1.10 MB)

Creating new dimensions in the world of chromatography

SiELC Primesep - Pharmaceutical Analysis Brochure (477.59 kB)

Solving problems of pharmaceutical HPLC analysis using Primesep columns

SiELC Primesep - Separation of Ions Brochure (293.32 kB)

New alternative to ion chromatography