SHARC HPLC Colums from SiELC

SHARC 1 is the first commercially available column whose primary separation mode is hydrogen bonding. The stationary phase is a hydrogen bond acceptor which interacts with electronegative atoms of analyte molecules. This unique column technology enables the separation of polar molecules of similar structure such as isomers and related impurities.

SHARC All pictures shown are for illustration purpose only. Actual product may vary.


SHARC™ HPLC columns are the latest, innovative column from SIELC Technologies, the inventors of Primesep®.

SHARC™ columns are the first commercially available in which the primary separation mode is hydrogen bonding and use the hydrogen bonding interaction of hydrogen atoms within the stationary phase with analyte molecules containing electronegative atoms such as oxygen, nitrogen, fluorine.

This is typically a weak interaction, especially when the separation is performed in aqueous solution. However, used in conjunction with purely organic eluent systems, these hydrogen bonding interactions can be exploited to achieve alternative selectivity than that achieved with reversed phase, normal phase or other mixed mode separations.