Agilent Bio MAb

Agilent Bio MAb HPLC Columns

Thorough characterization of monoclonal antibodies includes the identification and monitoring of acidic and basic isoforms. The Agilent Bio MAb HPLC columns feature a unique resin specifically designed for high-resolution charge-based separations of monoclonal antibodies.

Bio MAb columns are available in 1.7 µm, 3 µm, 5 µm, and 10 µm sizes, providing higher resolution with the smaller particles. The Bio MAb column features a highly uniform, densely packed, weak cation exchange layer. This layer of the Bio MAb column is chemically bonded to the hydrophilic, polymeric coating of the Bio MAb column.

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Part Number	Short Description	Phase	Particle Size	ID	Length	Pore Size	Type	Price
5190-2402	Agilent Bio MAb, NP1.7, 4 x 10mm, SS Guard	Agilent Bio MAb	1.7 um	4.0 mm	10 mm	Non-porous	SS Guard	£660.00
5190-2401	Agilent Bio MAb, NP1.7, 4.6 x 50mm, SS Column	Agilent Bio MAb	1.7 um	4.6 mm	50 mm	Non-porous	SS Column	£1,320.00
5190-2419	Agilent Bio MAb, NP10, 2.1 x 250mm, PK Column	Agilent Bio MAb	10 um	2.1 mm	250 mm	Non-porous	Peek Column	£1,665.00
5190-2420	Agilent Bio MAb, NP10, 2.1 x 50mm, PK Guard	Agilent Bio MAb	10 um	2.1 mm	50 mm	Non-porous	PEEK Guard	£722.00
5190-2414	Agilent Bio MAb, NP10, 4 x 10mm, SS Guard	Agilent Bio MAb	10 um	4.0 mm	10 mm	Non-porous	SS Guard	£472.00
5190-2415	Agilent Bio MAb, NP10, 4.6 x 250mm, PK Column	Agilent Bio MAb	10 um	4.6 mm	250 mm	Non-porous	Peek Column	£1,508.00
5190-2413	Agilent Bio MAb, NP10, 4.6 x 250mm, SS Column	Agilent Bio MAb	10 um	4.6 mm	250 mm	Non-porous	SS Column	£1,346.00
5190-2416	Agilent Bio MAb, NP10, 4.6 x 50mm, PK Guard	Agilent Bio MAb	10 um	4.6 mm	50 mm	Non-porous	PEEK Guard	£722.00
5190-2404	Agilent Bio MAb, NP3, 4 x 10mm, SS Guard	Agilent Bio MAb	3 um	4.0 mm	10 mm	Non-porous	SS Guard	£597.00
5190-2403	Agilent Bio MAb, NP3, 4.6 x 50mm, SS Column	Agilent Bio MAb	3 um	4.6 mm	50 mm	Non-porous	SS Column	£1,194.00
5190-6884	Agilent Bio MAb, NP5, 10 x 250mm, SS Column	Agilent Bio MAb	5 um	10.0 mm	250 mm	Non-porous	SS Column	£5,812.00
5190-2411	Agilent Bio MAb, NP5, 2.1 x 250mm, PK Column	Agilent Bio MAb	5 um	2.1 mm	250 mm	Non-porous	Peek Column	£1,917.00
5190-2412	Agilent Bio MAb, NP5, 2.1 x 50mm, PK Guard	Agilent Bio MAb	5 um	2.1 mm	50 mm	Non-porous	PEEK Guard	£942.00
5190-6885	Agilent Bio MAb, NP5, 21.2 x 250mm, SS Column	Agilent Bio MAb	5 um	21.2 mm	250 mm	Non-porous	SS Column	£18,875.00
5190-2406	Agilent Bio MAb, NP5, 4 x 10mm, SS Guard	Agilent Bio MAb	5 um	4.0 mm	10 mm	Non-porous	SS Guard	£534.00
5190-2407	Agilent Bio MAb, NP5, 4.6 x 250mm, PK Column	Agilent Bio MAb	5 um	4.6 mm	250 mm	Non-porous	Peek Column	£1,759.00
5190-2405	Agilent Bio MAb, NP5, 4.6 x 250mm, SS Column	Agilent Bio MAb	5 um	4.6 mm	250 mm	Non-porous	SS Column	£1,570.00
5190-2408	Agilent Bio MAb, NP5, 4.6 x 50mm, PK Guard	Agilent Bio MAb	5 um	4.6 mm	50 mm	Non-porous	PEEK Guard	£942.00

Features

A packing support composed of a rigid, spherical, highly cross-linked polystyrene divinylbenzene (PS/DVB) non-porous bead
Particles grafted with a hydrophilic, polymeric layer, virtually eliminating non-specific binding of antibody proteins
A different process is used to layer the weak cation-exchange phase to the particle making it a higher density than the Agilent Bio WCX column particles
Specifically designed for the separation of charge isoforms of monoclonal antibodies

Specifications

	Agilent Bio MAb
Bonded Phase	Weak Cation-Exchange (carboxylate)
ID	2.1 and 4.6 mm
Particle Size	1.7, 3, 5 and 10 µm
pH Stability	2 - 12
Operating Temperature Limit	80 ºC
Flow Rate	0.1 - 1 mL/min

Literature

Agilent Bio HPLC Columns (26.00 MB)

Your essential resource for biomolecule analysis

Agilent Bio MAb Data Sheet (37.22 kB)

Data sheet for the Agilent Bio MAb columns