Daicel CROWNPAK Crown Ether Chiral Columns
Daicel CROWNPAK CR(+) and CR(-) columns are packed with crown ether chiral stationary phases. They are designed for separation of chiral amino acids and other small molecules containing a primary amine group on the chiral centre.
CROWNPAK CR-I(+) and CR-I(-) feature immobilized selectors to extend the range of solvents used for mobile phases, enhancing enantioselective resolution of chiral compounds.
- Chiral recognition achieved when a complex is formed between the crown ether and an ammonium ion (-NH3+) from a sample, under acidic conditions
- Can resolve amino acids and compounds bearing a primary amino group near the chiral centre
- With CROWNPAK CR(+), the D-form of amino acids always elutes in first position, using CROWNPAK CR(-) will result in an inversion of the elution order
- Use of the immobilised CROWNPAK CR-I(+) & CR-I(-) selectors allows a wider range of solvents and also provides longer column life time
| CROWNPAK CR(+) | CROWNPAK CR(-) | CROWNPAK CR-I(+) | CROWNPAK CR-I(-) | |
| USP | L66 | L117 | - | - |
| Particle size | 5 µm | 5 µm | 5 µm | 5 µm |
| Type | Crown ether | Crown ether | Immobilised crown ether | Immobilised crown ether |
| Separation mode | reversed phase | reversed phase | reversed phase and normal phase | reversed phase and normal phase |
| Shipping solvent | water/methanol (95/5) | water/methanol (95/5) | water/methanol (95/5) | water/methanol (95/5) |
| Temperature range | -5 - 50°C | -5 - 50°C | -5 - 40°C | -5 - 40°C |
Daicel Chiral Selectors Poster
(279.53 kB)
Structures of commercially available Daicel chiral stationary phases