YMC-Pack Pro C4 HPLC Columns
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YMC-Pack Pro C4 Analytical HPLC Columns
With Pro C4, YMC offers a stationary phase based on the well-known ultra pure silica of the ProFamily. Compared to a C18 phase with the same eluent, C4 phases are less hydrophobic and gives shorter retention times for non-polar compounds while the retention time of polar analytes are virtually unaffected. This makes the Pro C4 an interesting alternative especially when short analysis times are required.
The YMC-Pack Pro C4 columns offer a unique balance of hydrophobicity and speed, making them an excellent choice for fast chromatography of polar organic molecules, particularly peptides and small proteins. Based on YMC’s high-purity silica, these columns are tailored to provide efficient separation with reduced retention times compared to more hydrophobic phases.
Features
- C4 stationary phase with USP L26 desingation
- Designed with shorter butyl groups to provide less hydrophobic interactions than C8 or C18 columns
- Delivers faster elution of non-polar compounds while maintaining adequate retention for polar analytes
- Proprietary endcapping technology minimises the effect of residual silanols on peak shapes, ensuring symmetrical peaks for basic compounds
- Ideal for applications requiring quick run times without sacrificing separation quality, particularly valuable in high-throughput environments
- Suited for the rapid analysis of peptides, small proteins, and other polar organic compounds in pharmaceutical and biochemical research
- Available with ultra-pure fully porous particles in 3 µm and 5 µm sizes
- Fully scalable up to preparative dimensions
- Guard columns recommended to increase the analytical column’s lifetime
Specification
| YMC-Pack Pro C4 | |
| Bonded Phase | C4 |
| Particle Type | Fully Porous |
| Particle Size | 3 µm, 5 µm |
| Pore Size | 120 Å |
| Surface Area | 330 m2/g |
| Endcapped | Yes |
| Carbon Load | 7% |
| Maximum Temperature | 50°C |
| pH Range | 2 - 7.5 |
| Hardware | Stainless Steel |
| USP Designation | L26 |
