Bondesil Bulk Sorbents and Salts from Agilent
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Agilent’s Bondesil bulk sorbents and salts offer high-purity solutions for large-scale sample preparation, including clean-up, purification, custom SPE cartridge packing, and manual preparation of QuEChERS tubes. These materials – identical to those used in Bond Elut SPE cartridges – are available in bulk formats for scalable workflows and method development. Offered in silica, carbon, and polymeric chemistries, with irregular particle sizes of 40 or 120 µm, Bondesil sorbents provide ultra selective chemical separation across a broad analyte range.
Features
- Clean sorbents ensure low-background, high-purity bulk extractions
- Consistent bonding chemistries enable reproducible performance across batches
- Available in various particle sizes for method flexibility and scalable workflows
- Suitable for SPE and QuEChERS applications
- Multi-kilogram quantities available upon request to support high-throughput laboratories
Specification
| Phase | Description |
| Polymeric | |
| Bondesil Plexa | Amide-free, hydroxylated surface on PS-DVB core for minimal protein binding and clean extracts |
| Bondesil PPL | Modified PS-DVB polymer with high polarity retention; ideal for viscous or particle-laden samples |
| Bondesil ENV | Unfunctionalised PS-DVB polymer with high capacity and fast flow; handles polar analytes and large molecules |
| Reversed Phase | |
| Bondesil C18 | Most hydrophobic bonded silica with broad-spectrum retention; ideal for nonpolar compounds |
| Bondesil C18 OH | Non-endcapped variant for enhanced retention of basic compounds and metabolite profiling |
| Bondesil C18 EWP | 500 Å pore size for large biomolecule extraction, protein desalting, and nucleotide separation |
| Bondesil C8 | Less retentive than C18; ideal for moderately non-polar compounds |
| Bondesil C2 | Short-chain non-polar phase used when retention is too strong on C18 or C8 |
| Bondesil PH | Non-polar bonded phase offering enhanced retention for planar, conjugated organics |
| Normal Phase | |
| Bondesil SI | Highly polar, unbonded silica phase effective in separating closely related structural analogues |
| Bondesil CN-U | Unendcapped cyano phase for highly polar analytes in nonpolar sample matrices |
| Ion-Exchange | |
| Bondesil SAX | Strong anion exchanger, ideal for extracting carboxylic acids and strongly acidic compounds |
| Bondesil SCX | Strong cation exchanger with both ionic and hydrophobic interaction potential; excellent for aqueous or buffered systems |
| Bondesil PRS | Strong cation exchanger with hydrogen bonding capacity; suitable for weak cationic species |
| Bondesil CBA | Midpolarity, weak cation exchanger with broader compatibility for quaternary amines |
| Bondesil NH₂ | Weak anion exchanger for separating strong anions and structural isomers |
| Bondesil DEA | Medium polarity weak anion exchanger; lower capacity than NH2 |
| Bondesil PSA | Dual amino-functional sorbent with high carbon load; strong for polar compound retention |
| Inorganic | |
| Alumina | Highly polar sorbent with superior stability under high pH conditions compared to unfunctionalised silica |
| Florisil (FL) | Magnesia-loaded silica; excellent for polar compound extraction from viscous or nonpolar matrices |
| Speciality | |
| Bond Elut Carbon | Optimised for pigment and small organic residue removal; strong retention across diverse analytes |
| Bondesil EnvirElut | Designed for extracting a wide range of analytes from aqueous matrices |
| Bondesil PBA | Phenylboronic acid phase with strong affinity for cis-diol analytes via covalent bonding |