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SiELC Primesep AB HPLC Columns

SiELC Primesep AB is trimodal HPLC column with a C12 hydrophobic chain and cation-exchange and anion exchange groups on the surface. It provides enhanced retention of strongly acidic and basic compounds through an ion-exchange mechanism and retains neutral compounds using a reversed phase mechanism. The Primesep AB is ideal for the simultaneous analysis of acidic, basic, and neutral compounds using simple method conditions.

Part Number Product Description Price Qty
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Features

  • Primesep AB is a reversed phase column with embedded acidic and basic ion-pairing groups
  • Improves retention of strongly acidic and basic compounds through ion-exchange mechanism
  • Retains neutral compounds by reversed phase mechanism
  • Offers mobile phase compatibility with LC-MS
  • Resistant to dewetting in 100% aqueous mobile phase
  • Scalable from capillary to prep
  • Guard columns connect directly to columns and do not require any additional holders

Specification

  Primesep AB
Mode Mixed-Mode
Phase Type Acidic and basic ion-pairing groups embedded into long ligand chains
Particle Type Fully Porous
Particle Size 5 µm
Pore Size 100 Å
Temperature Range 0 - 50°C
pH Limit 1.5 - 7.0
Recommended pH Operating Range 2.0 - 6.5
Pressure Limit 345 bar

Literature

Creating new dimensions in the world of chromatography
Solving problems of pharmaceutical HPLC analysis using Primesep columns
New alternative to ion chromatography