Advion-Interchim puriFlash 5.050
The puriFlash 5.050 from Advion-Interchim Scientific is a versatile chromatography system designed to accommodate both flash and preparative purification workflows within a single platform. Designed for laboratories seeking high-performance separations, it supports transitions between normal phase and reversed phase chromatography, including compatibility with reusable stainless-steel columns packed with low-particle-size media – enabling higher resolution and improved compound purity.
With a maximum operating pressure of 50 bar, the system is well suited for more demanding preparative tasks while maintaining the rapid throughput and ease of flash chromatography. Integrated wash disc technology enhances instrument longevity by enabling back-flushing of pump heads with water, which reduces the risk of crystallisation from mobile phase additives – a common issue in routine purifications.
The puriFlash 5.050 incorporates multiple detection modes, including UV, ELSD, and mass detection, to ensure accurate compound tracking and improved recovery, particularly when working with complex mixtures. Advanced safety features, such as solvent level sensors and leak detection, protect both user and system from operational errors and equipment wear.
Control and data handling are streamlined through the ClearPeak software on a 15 inch touchscreen, enabling real-time monitoring, simplified method development, and automatic consumable recognition via RFID. The integrated Genius interface supports AI-assisted method creation, including TLC-to-method conversion, improving efficiency and reproducibility. With remote monitoring and mobile app support, users can oversee purifications from anywhere. Compact yet highly capable, the puriFlash 5.050 is well suited for both routine and advanced chromatographic applications.
All pictures shown are for illustration purpose only. Actual product may vary.
Features
- ClearPeak Software Control – Full system management with intuitive interface for method development, monitoring, and automation
- 15" Touchscreen & Remote Monitoring – Real-time control with remote access for flexible workflow management
- Smartphone App Integration – Compatible with TLC to Flash & Prep app for seamless method transfer from TLC plates
- Multi-Wavelength UV Detection – 200–400 nm range with simultaneous multi-wavelength and collective scanning
- Column Compatibility – Supports flash columns (F0004 to F3000) and preparative columns up to 80 mm (3") internal diameter
- High Capacity Racks – Includes 3 long racks with space for up to 132 test tubes
- High Flow Rate – Up to 250 ml/min for rapid processing of large sample volumes
- High Pressure Capability – Operates up to 50 bar for efficient preparative and reversed phase chromatography
- Performance Upgrade Packs – Optional UVextended and iELSD modules available for enhanced detection sensitivity and compound coverage
Specification
| puriFlash 5.050 | |
| Pump | |
| Flow rate | 250 mL/min |
| Max pressure | 50 bar |
| Quaternary gradient | yes |
| Air purge | yes |
| Washing discs | yes |
| Pump washing discs (pack) | no |
| Detector | |
| UV: 200 - 400 nm multi wavelength & scan collection | yes |
| UV: 200 - 800 nm multi wavelength & scan collection | pack-UVextended |
| Spectral view and purity confirmation | yes |
| iELSD Detection (pack) | pack-iELSD |
| Injection | |
| 4 port electrical valve | no |
| 6 port electrical valve with loop | yes |
| 6 port + 10 port electrical valves with loop | no |
| Injection mode: liquid - dry-load | yes |
| Column Selection Valve | |
| 6 port electrical valve | no |
| System Optimisation | |
| Tubing after pump | 1/8" x 1.6 mm ID |
| Flow cell: optical length/volume | 0.3 mm/40 µL |
| Column Holder | |
| Integrated | yes |
| Pre-column holder | yes |
| Fraction Collector | |
| Reglular collector | 3 racks Gen5 132 tubes 18 x 150 mm |
| Unit Control | |
| Touch screen 15" | yes |
| USB | 8 |
| RJ45 | yes |
| Safety | |
| Leak detection (pump, FC, iELSD, holders) | yes |
| Solvent tray with drainage system | yes |
| Collector with drainage system | yes |
| Solvent and waste level monitoring | yes |
| RFID | yes |
| Fume enclosure | yes |
| Size | Width: 40 cm Depth: 51 cm Height: 75 cm |