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Crawford Scientific

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HPLC Columns

HPLC continues to be developed and improved upon. These advancements have necessitated a wider selection in the materials and components that we use, meaning there are now tens-of-thousands of columns available to HPLC practitioners. While having this selection is advantageous in many ways, it comes with a huge list of considerations that must be addressed when deciding which column is right for your separation.

We want to share our knowledge on the subject, to make the process of buying an HPLC column less confusing. 

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  1. Agilent Altura Poroshell 120 PFAS Column With Ultra Inert Technology

    09 Mar 2026

    Agilent Altura Poroshell 120 PFAS Column With Ultra Inert Technology

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  2. HALO® OLIGO C18 Columns: Advanced Separation for Oligonucleotide Analysis

    14 Jan 2026

    HALO® OLIGO C18 Columns: Advanced Separation for Oligonucleotide Analysis

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  3. HALO® PFAS Solutions – Expanded Column Range for Analysing Persistent Contaminants

    13 Nov 2025

    HALO® PFAS Solutions – Expanded Column Range for Analysing Persistent Contaminants

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  4. Halo Selectivity

    17 Oct 2025

    The HALO® Selectivity Landscape

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  5. Agilent AdvanceBio Surfactant Profiling HPLC Columns – Improving Surfactant Analysis in Biopharma

    24 Sep 2025

    Agilent AdvanceBio Surfactant Profiling HPLC Columns – Improving Surfactant Analysis in Biopharma

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  6. Advantages and Applications of Passivated HPLC Hardware for Large and Small Molecule Analysis - YMC Accura Triart & AMT Halo Inert Column Ranges

    30 Jul 2025

    Advantages and Applications of Passivated HPLC Hardware for Large and Small Molecule Analysis - YMC Accura Triart & AMT Halo Inert Column Ranges

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  7. AdvanceBio SEC: Overcoming Challenges in Modern Biotherapeutic Aggregate Analysis

    15 Jul 2025

    AdvanceBio SEC: Overcoming Challenges in Modern Biotherapeutic Aggregate Analysis

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  8. HALO® Elevate versus Hybrid Silica Particles

    20 Jun 2025

    HALO® Elevate versus Hybrid Silica Particles

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  9. Lipid Nanoparticles Analysis

    28 May 2025

    Lipid Nanoparticles Analysis

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  10. Introducing HALO® PCS HPLC Columns – Positively Exceptional Performance for Basic Compounds!

    22 May 2025

    Introducing HALO® PCS HPLC Columns – Positively Exceptional Performance for Basic Compounds!

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  11. Choosing Between Fully Porous and Superficially Porous Particles in HPLC: Performance, Pressure, and Practicality

    07 May 2025

    Choosing Between Fully Porous and Superficially Porous Particles in HPLC: Performance, Pressure, and Practicality

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  12. LC Column Strategies for Ultra-Short Chain PFAS Analysis Using LC-MS

    24 Apr 2025

    LC Column Strategies for Ultra-Short Chain PFAS Analysis Using LC-MS

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