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Agilent AdvanceBio RP-mAb Columns

AdvanceBio RP-mAb HPLC Columns from Agilent

Agilent AdvanceBio RP-mAb columns are designed to optimize the performance of intact and reduced mAb analysis when analyzing monoclonal antibodies for biopharma discovery, development, and QA/QC applications.

Analysis of intact and reduced monoclonal antibodies are critical measurements for characterizing therapeutic proteins and understanding their efficacy and stability. Poor chromatographic separations can result in rework and even compromise the accuracy of the characterization.

Based on Poroshell technology with unique engineering for pore size and bonded phases, AdvanceBio RP-mAb columns deliver higher resolution and faster run times to provide accurate, reproducible results. Available in a range of chemistries – SB-C8, C4, and diphenyl.

Agilent AdvanceBio RP-mAb columns are designed to optimize the performance of intact and reduced mAb analysis when analyzing monoclonal antibodies for biopharma discovery, development, and QA/QC applications. Analysis of intact and reduced monoclonal antibodies are critical measurements for characterizing therapeutic proteins and understanding their efficacy and stability. Poor chromatographic separations can result in rework and even compromise the accuracy of the characterization. 

Based on Poroshell technology with unique engineering for pore size and bonded phases, AdvanceBio RP-mAb columns deliver higher resolution and faster run times to provide accurate, reproducible analysis and results. These RP-mAb columns are available in a range of chemistries – SB-C8, C4, and diphenyl.

Part Number Short Description Phase Particle Size ID Length Pore Size Type Price Qty
795775-904 AdvanceBio RP-mAb C4 2.1 x 100mm 3.5um Column AdvanceBio RP-mAb C4 3.5 um 2.1 mm 100 mm 450 A Column
£760.00
793775-904 AdvanceBio RP-mAb C4 2.1 x 150mm 3.5um Column AdvanceBio RP-mAb C4 3.5 um 2.1 mm 150 mm 450 A Column
£828.00
799775-904 AdvanceBio RP-mAb C4 2.1 x 50mm 3.5um Column AdvanceBio RP-mAb C4 3.5 um 2.1 mm 50 mm 450 A Column
£599.00
797775-904 AdvanceBio RP-mAb C4 2.1 x 75mm 3.5um Column AdvanceBio RP-mAb C4 3.5 um 2.1 mm 75 mm 450 A Column
£681.00
795975-904 AdvanceBio RP-mAb C4 4.6 x 100mm 3.5um Column AdvanceBio RP-mAb C4 3.5 um 4.6 mm 100 mm 450 A Column
£760.00
793975-904 AdvanceBio RP-mAb C4 4.6 x 150mm 3.5um Column AdvanceBio RP-mAb C4 3.5 um 4.6 mm 150 mm 450 A Column
£828.00
799975-904 AdvanceBio RP-mAb C4 4.6 x 50mm 3.5um Column AdvanceBio RP-mAb C4 3.5 um 4.6 mm 50 mm 450 A Column
£595.00
795775-944 AdvanceBio RP-mAb Diphenyl 2.1 x 100mm 3.5um Column AdvanceBio RP-mAb Diphenyl 3.5 um 2.1 mm 100 mm 450 A Column
£760.00
793775-944 AdvanceBio RP-mAb Diphenyl 2.1 x 150mm 3.5um Column AdvanceBio RP-mAb Diphenyl 3.5 um 2.1 mm 150 mm 450 A Column
£828.00
799775-944 AdvanceBio RP-mAb Diphenyl 2.1 x 50mm 3.5um Column AdvanceBio RP-mAb Diphenyl 3.5 um 2.1 mm 50 mm 450 A Column
£599.00
797775-944 AdvanceBio RP-mAb Diphenyl 2.1 x 75mm 3.5um Column AdvanceBio RP-mAb Diphenyl 3.5 um 2.1 mm 75 mm 450 A Column
£681.00
795975-944 AdvanceBio RP-mAb Diphenyl 4.6 x 100mm 3.5um Column AdvanceBio RP-mAb Diphenyl 3.5 um 4.6 mm 100 mm 450 A Column
£760.00
793975-944 AdvanceBio RP-mAb Diphenyl 4.6 x 150mm 3.5um Column AdvanceBio RP-mAb Diphenyl 3.5 um 4.6 mm 150 mm 450 A Column
£828.00
799975-944 AdvanceBio RP-mAb Diphenyl 4.6 x 50mm 3.5um Column AdvanceBio RP-mAb Diphenyl 3.5 um 4.6 mm 50 mm 450 A Column
£595.00
785775-906 AdvanceBio RP-mAb SB-C8 2.1 x 100mm 3.5um Column AdvanceBio RP-mAb SB-C8 3.5 um 2.1 mm 100 mm 450 A Column
£760.00
783775-906 AdvanceBio RP-mAb SB-C8 2.1 x 150mm 3.5um Column AdvanceBio RP-mAb SB-C8 3.5 um 2.1 mm 150 mm 450 A Column
£828.00
789775-906 AdvanceBio RP-mAb SB-C8 2.1 x 50mm 3.5um Column AdvanceBio RP-mAb SB-C8 3.5 um 2.1 mm 50 mm 450 A Column
£599.00
787775-906 AdvanceBio RP-mAb SB-C8 2.1 x 75mm 3.5um Column AdvanceBio RP-mAb SB-C8 3.5 um 2.1 mm 75 mm 450 A Column
£681.00
785975-906 AdvanceBio RP-mAb SB-C8 4.6 x 100mm 3.5um Column AdvanceBio RP-mAb SB-C8 3.5 um 4.6 mm 100 mm 450 A Column
£760.00
783975-906 AdvanceBio RP-mAb SB-C8 4.6 x 150mm 3.5um Column AdvanceBio RP-mAb SB-C8 3.5 um 4.6 mm 150 mm 450 A Column
£828.00
789975-906 AdvanceBio RP-mAb SB-C8 4.6 x 50mm 3.5um Column AdvanceBio RP-mAb SB-C8 3.5 um 4.6 mm 50 mm 450 A Column
£595.00
  • 3.5 µm superficially porous particles with 450 Å wide pores increase mAb resolution while maintaining compatibility with all LC instruments
  • Shorter analysis times compared to columns packed with fully porous particles of the same size
  • Robust Poroshell packed bed and 2 µm inlet frit extend column lifetime by helping prevent inlet blockage
  • Flexible method development with range of chemistries including SB-C8, C4, and diphenyl
  AdvanceBio RP-mAb C4 AdvanceBio RP-mAb SB-C8 AdvanceBio RP-mAb Diphenyl
Bonded Phase C4 SB-C8 Diphenyl
Particle Type Superficially Porous Superficially Porous Superficially Porous
Particle Size 3.5 µm  3.5 µm  3.5 µm
Pore Size 450 Å 450 Å 450 Å
Temperature Limit 90°C 90°C 90°C
pH range 1 - 8 1 - 8 1 - 8
Pressure Limit 600 bar 600 bar 600 bar
Agilent AdvanceBio RP-mAb columns brochure (1.18 MB)

Resolve mAbs faster and better with Agilent AdvanceBio RP-mAb columns

Intact and Subunit Purity Application Compendium (3.08 MB)
Collection of Agilent app notes for intact and subunit analysis
AdvanceBio Reversed Phase Columns White Paper (3.07 MB)
Better characterization of biomolecules using Agilent AdvanceBio reversed phase columns
Agilent Bio HPLC Columns (26.00 MB)

Your essential resource for biomolecule analysis

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