Dynamic Axial Compression (DAC) Columns

Dynamic Axial Compression (DAC) columns are automated self-packing preparative chromatography systems designed to maintain a uniformly compressed and stable sorbent bed throughout use, ensuring high performance and reproducible separations from laboratory to pilot and industrial scales. By combining the packing and chromatographic functions within a single unit, DAC columns allow straightforward, cost-effective refilling of packing media while preventing bed collapse and promoting long-term durability. Their continuous axial compression supports consistent flow characteristics, efficient use of small-particle sorbents and reliable scalability across demanding purification processes.