Advion-Interchim puriFlash 5.015-XL

The puriFlash 5.015-XL is a high-capacity flash chromatography system developed to meet the demands of kilo-lab and process-scale purification. Engineered for robustness and reproducibility, it is suited to environments where consistent recovery, throughput, and system uptime are essential.

Designed for semi-continuous purification of compounds at the several-hundred-gram scale, the system enables efficient scale-up from laboratory to process development. With a maximum flow rate of 825 mL/min and compatibility with Flash column formats up to F3000, the 5.015-XL facilitates the rapid processing of large sample loads with a reduced number of cycles, supporting both productivity and purification performance.

The system integrates ClearPeak software for operational control and monitoring. Key safety and process features include real-time solvent level tracking, automated column protection against drying, and leak detection. These functions help to safeguard both product integrity and system reliability during extended runs.

The puriFlash 5.015-XL supports a wide range of compound classes and purification protocols, making it suitable for applications across synthetic chemistry, natural products isolation, and preparative workflows involving complex mixtures. It is particularly valuable in settings where high sample throughput and reproducible performance are required under scale-up conditions.

The puriFlash 5.015-XL offers a technically advanced solution for large-batch flash purification, combining high flow rates, broad column compatibility, and integrated process safeguards to support consistent, high-quality separations at scale.