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ePrep® ONE Sample Preparation Workstation

The ePrep® ONE Sample Preparation Workstation from ePrep, is an advanced fully automated robotic platform purpose built for chromatography sample preparation. Designed to address sample preparation as the traditional weak link in analytical workflows, it delivers precise, reproducible and compliant results across a wide range of industries including life sciences, environmental, food, clinical, forensic and pharmaceutical laboratories.

Unlike conventional pipetting systems, ePrep ONE uses analytical syringes to achieve highly accurate liquid handling with volume reproducibility of ≤0.5%. It automates dilution, aliquoting, standard addition, filtering, SPE, µSPE, and liquid-liquid extraction within a single integrated workflow. Features such as robotic syringe exchange, an integrated wash station to minimise carryover, and direct dispensing into sealed autosampler vials ensure sample integrity and reduced variability. 

The ePrep ONE intuitive drag-and-drop software enables rapid method development, validation and secure data logging, allowing workflows to be programmed in minutes. A 21CFR Part11 compliant version of the software is available. With flexible deck configurations, offline operation and optional accessories for advanced extraction and filtering, ePrep ONE supports both small and medium batch sizes, improving laboratory efficiency, reducing solvent consumption and enabling reliable unattended operation day and night. 

 

Features

  • Automated Workflow Capability – Supports dilution, aliquoting, standard addition, filtering, µSPE, SPE, and liquid-liquid extraction for streamlined sample preparation
  • Enhanced Efficiency & Accuracy – Reduces variability while improving consistency across virtually any workflow
  • Precision Syringe Technology – Uses analytical syringes to ensure highly accurate and precise liquid handling
  • High Reproducibility – Achieves volume reproducibility of ≤0.5% for reliable results
  • Robotic Syringe Exchange – Automated syringe change function for uninterrupted operation
  • Integrated Wash Station – Minimises carryover and maintains sample integrity
  • Direct Vial Dispensing – Enables dispensing directly into sealed autosampler vials
  • Flexible Software Platform – Drag-and-drop method development with validation tools and secure data logging
  • Regulatory Compliance – Optional software version compliant with 21 CFR Part 11
  • Rapid Setup – Simple and fast workflow configuration for immediate use
  • Unattended Operation – Capable of running samples overnight to maximise productivity
  • Reduced Environmental Impact – Minimises solvent consumption and waste generation
  • Increased Lab Productivity – Frees up staff time for higher value tasks
  • Modular Accessories – Wide range of tools and accessories to suit diverse sample preparation needs
  • Virtual Demonstration – Demo available upon request – contact us!

Specification

  ePrep ONE®
LIQUID HANDLING AND SAMPLE PREPARATION
Typical Syringe Precision & Accuracy*
  • 10 mL: Accuracy ±1.0%, RSD 1.0%
  • 1 mL: Accuracy ±1.0%, RSD 1.0%
  • 100 μL: Accuracy ±1.5%, RSD 1.0%
  • 10 μL: Accuracy ±3.0%, RSD 2.0%
Carryover For multi-use liquid handling tools an integrated wash station is used to control carryover. 
Carryover achieved depends on the syringe type, sample characteristics and user-settable parameters in the software.
Syringes Volume Range
  • Minimum volume: 1 μL (precision of lower volumes based on operating conditions)
  • Maximum volume: >10 mL per dispenses with unlimited volume achievable using multiple aspirate/dispense cycles
OPERATIONAL INFORMATION
Deck Capacity Total 16 (16P) x 1P deck positions available. 
Space is used to accommodate Adapter Plates existing in variable sizes from 1P-6P configurations.
Laboratory A well ventilated and climate controlled environment is suggested. 
With sealed vials, a cover is not required. 
If using toxic materials, take appropriate safety precautions.
Control Computer & Software Laptop Computer (supplied) including ePrep ONE workflow development and control software (English Only) and lifetime updates
Connectivity Tablet to Instrument USB
Wash Station Deck mounted syringe Wash Station.
Three individual pumps control the wash liquid supply, the wash waste removal and removal of on deck accessory waste. 
External solvent and waste reservoirs are not supplied.
Asset Identification RFID identification on syringes, tools, and racks
SYSTEM INFORMATION
Instrument Dimensions (L x W x H)     1370 mm x 694 mm x 743 mm
Weight 65 kg
Voltage 24 V, 221 W, 9.2 A DC Power Pack; 100-240 Volt AC input. 
Requires country specific IEC C13 power cable (supplied separately).
ePrep Connection ports 3 x Serial Comms, 4 x Digital Output, 4 x Digital Input, 4 x Relay
Operating Temperature 10-35°C, 0-80% relative humidity
Operating Sound Level Typical 80 dB
Compliance CE, FCC, IC, RCM, RoHS, Safety EN 61010, EMC 61326
Warranty 12 months
TYPICAL APPLICATION CONFIGURATIONS
Details available from ePrep for instrument, accessories and consumables configuration for challenging applications including Liquid-Liquid Extractions, Soil-Liquid Extractions, Syringe Filtering, SPE and µSPE and Vialling

* Configuration Teflon Tipped Plunger and 80 mm and 103 mm Needles

 

Literature

Overview of the ePrep ONE workstation
Full range of supporting products for the ePrep ONE workstation
Application note detailing PFAS in soil analysis with magnetic stirring
Application note describing calibration standard preparation for PFAS analysis using the ePrep ONE
Application note describing calibration standard preparation using the ePrep ONE

Videos