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Gilson EXTRACTMAN

The EXTRACTMAN magnetic bead extraction platform from Gilson is designed for rapid and gentle isolation of target proteins using Exclusion-based Sample Preparation (ESP) technology. Unlike conventional magnetic bead workflows that rely on repeated pipetting and liquid transfers, EXTRACTMAN moves bead–analyte complexes through immiscible phases using surface tension and hydrophobic interactions. This approach minimises shear forces and sample handling, helping to preserve weak or transient molecular interactions during purification.

EXTRACTMAN is commonly used for co-immunoprecipitation (Co-IP) and other affinity-based workflows where sample integrity is critical. By pairing ESP with non-porous paramagnetic beads, the platform enables efficient purification without lengthy wash steps or sample dilution. The slide-based mechanism allows up to four samples to be processed in parallel and is compatible with a wide range of commercially available magnetic bead kits for protein, DNA, RNA, and mRNA isolation.

Features

  • Exclusion-based Sample Preparation (ESP) Technology – Uses surface tension and hydrophobic properties to move bead–analyte complexes through wash phases without liquid transfer
  • Gentle Sample Handling – Reduces shear stress by eliminating pipette-based wash steps, supporting preservation of weakly bound or transient interactions
  • Slide-Based Extraction Mechanism – Enables simultaneous processing of up to four samples via a simple manual sliding action
  • Compatibility with Commercial Bead Kits – Functions as a universal platform for a wide range of paramagnetic bead-based reagents and assays
  • Reduced Wash Time – Achieves purification in seconds rather than minutes by excluding unbound contaminants instead of repeatedly washing beads
  • Minimal Sample Disturbance – Extracts analytes without dilution or significant alteration of the original sample composition
  • Versatile Application Range – Demonstrated use in isolation of proteins, DNA, RNA, and mRNA from complex or crude biological extracts

Literature

Full guide to Gilson's range of liquid handling products
EXTRACTMAN Flyer (551.99 kB)
EXTRACTMAN offers a faster, gentler magnetic mixing approach for isolating target proteins
Set up and operation instructions for the Gilson EXTRACTMAN
Discover how the EXTACTMAN prevents cross-contamination

Videos