Altura HPLC columns from Agilent bring exceptional bio-inert liquid chromatography performance to a broad range of analytical applications. Combining the strength of stainless steel with Agilent’s advanced Ultra Inert coating, these columns eliminate metal–analyte interactions that cause adsorption, signal loss, and poor reproducibility. The result is a fully inert flow path that enhances analyte recovery, peak shape, and sensitivity. With rapid equilibration, long lifetime, and reliable consistency, Altura columns deliver superior performance for metal-sensitive and polar compounds across LC and LC-MS workflows.

The Altura Poroshell HILIC-Z column pairs Ultra Inert hardware with a zwitterionic stationary phase optimised for hydrophilic interaction chromatography (HILIC) of small, polar, and anionic analytes. Using the same proven media as the AdvanceBio MS Spent Media column, it employs superficially porous silica particles for fast, efficient separations and exceptional peak symmetry. Ideal for amino acid analysis, cell-culture metabolite profiling, and excipient characterisation, the HILIC-Z delivers high recovery and reproducibility without metal interference. Its bio-inert design ensures accurate, MS-compatible results for underivatised amino acids and other polar metabolites providing a robust, high-throughput solution for modern analytical and LC-MS laboratories.