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Altura Poroshell HPH-C18 Ultra Inert Columns from Agilent

Altura HPLC columns from Agilent deliver exceptional bio-inert performance and long-term stability for the most demanding liquid chromatography applications. Incorporating Agilent’s Ultra Inert coating, these columns eliminate metal–analyte interactions that cause peak tailing, signal loss, and inconsistent recovery. The result is a fully inert flow path that enables sharper peaks, higher sensitivity, and more accurate quantitation for metal-sensitive compounds. With rapid equilibration, superior reproducibility, and durable performance, Altura columns ensure reliable results across LC and LC/MS workflows.

The Altura Poroshell HPH-C18 is a high-performance reversed phase HPLC column designed for use under elevated pH conditions. It features Ultra Inert stainless steel hardware and a 1.9 µm superficially porous particle for outstanding efficiency and sensitivity. The hybrid particle design provides exceptional mechanical and chemical stability, supporting a pH range of 3–11 and temperatures up to 65 °C. Ideal for high-pH LC methods, this column offers improved selectivity, consistent peak shape, and extended lifetime – reducing downtime and replacement costs. The Altura Poroshell HPH-C18 delivers robust, reproducible separations and high-resolution performance, making it the optimal choice for laboratories requiring stability in high-pH workflows.

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Features

  • Ultra Inert Flow Path – Eliminates metal–analyte interactions for superior reproducibility and peak integrity
  • High-pH Compatibility – Operates reliably from pH 3–11, supporting a broad range of mobile phases
  • Hybrid Particle Technology – Enhances column ruggedness and longevity under demanding conditions
  • Superficially Porous Particles – Achieve high efficiency and resolution with reduced backpressure
  • Long Column Lifetime – Fewer replacements required due to robust particle and coating design
  • Wide Application Rage – Ideal for high-sensitivity separations in reversed phase and high-pH workflows

Specification

  Altura Poroshell HPH-C18
Bonded Phase C18
Particle Type Superficially Porous
Particle Size 1.9 µm
Pore Size 100 Å
Surface Area 95 m2/g
Maximum Temperature 65°C
pH Range 3 - 11
Pressure Limit 1200 bar
Hardware Ultra Inert Stainless Steel

Videos

Literature

Your essential resource for biomolecule analysis
User guide for Altura, AdvanceBio and Agilent Bio reversed phase HPLC columns
Perform rugged, fast LC with confidence
Choose the right particle size and bonded phase to achieve optimal separation for your samples
Agilent Altura HPLC columns with ultra inert technology for your most demanding applications
A comprehensive evaluation of inertness, stability, and analytical sensitivity