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Agilent Bio MAb Columns

Agilent Bio MAb HPLC Columns

Thorough characterization of monoclonal antibodies includes the identification and monitoring of acidic and basic isoforms. The Agilent Bio MAb HPLC columns feature a unique resin specifically designed for high-resolution charge-based separations of monoclonal antibodies.

Bio MAb columns are available in 1.7 µm, 3 µm, 5 µm, and 10 µm sizes, providing higher resolution with the smaller particles. The Bio MAb column features a highly uniform, densely packed, weak cation exchange layer. This layer of the Bio MAb column is chemically bonded to the hydrophilic, polymeric coating of the Bio MAb column.

Agilent Bio MAb columns feature a unique resin specifically designed for high-resolution charge-based separations of monoclonal antibodies. Bio MAb columns are available in 1.7 μm, 3 μm, 5 μm, and 10 μm sizes, providing higher resolution with the smaller particles. The Bio MAb column features a highly uniform, densely packed, weak cation exchange layer. This layer of the Bio MAb column is chemically bonded to the hydrophilic, polymeric coating of the Bio MAb column.

Part Number Short Description Phase Particle Size ID Length Pore Size Type Price Qty
5190-2402 Agilent Bio MAb, NP1.7, 4 x 10mm, SS Guard Agilent Bio MAb 1.7 um 4.0 mm 10 mm Non-porous SS Guard
£682.00
5190-2401 Agilent Bio MAb, NP1.7, 4.6 x 50mm, SS Column Agilent Bio MAb 1.7 um 4.6 mm 50 mm Non-porous SS Column
£1,364.00
5190-2419 Agilent Bio MAb, NP10, 2.1 x 250mm, PK Column Agilent Bio MAb 10 um 2.1 mm 250 mm Non-porous Peek Column
£1,720.00
5190-2420 Agilent Bio MAb, NP10, 2.1 x 50mm, PK Guard Agilent Bio MAb 10 um 2.1 mm 50 mm Non-porous PEEK Guard
£746.00
5190-2414 Agilent Bio MAb, NP10, 4 x 10mm, SS Guard Agilent Bio MAb 10 um 4.0 mm 10 mm Non-porous SS Guard
£487.00
5190-2415 Agilent Bio MAb, NP10, 4.6 x 250mm, PK Column Agilent Bio MAb 10 um 4.6 mm 250 mm Non-porous Peek Column
£1,558.00
5190-2413 Agilent Bio MAb, NP10, 4.6 x 250mm, SS Column Agilent Bio MAb 10 um 4.6 mm 250 mm Non-porous SS Column
£1,391.00
5190-2416 Agilent Bio MAb, NP10, 4.6 x 50mm, PK Guard Agilent Bio MAb 10 um 4.6 mm 50 mm Non-porous PEEK Guard
£746.00
5190-2404 Agilent Bio MAb, NP3, 4 x 10mm, SS Guard Agilent Bio MAb 3 um 4.0 mm 10 mm Non-porous SS Guard
£617.00
5190-2403 Agilent Bio MAb, NP3, 4.6 x 50mm, SS Column Agilent Bio MAb 3 um 4.6 mm 50 mm Non-porous SS Column
£1,233.00
5190-6884 Agilent Bio MAb, NP5, 10 x 250mm, SS Column Agilent Bio MAb 5 um 10.0 mm 250 mm Non-porous SS Column
£6,004.00
5190-2411 Agilent Bio MAb, NP5, 2.1 x 250mm, PK Column Agilent Bio MAb 5 um 2.1 mm 250 mm Non-porous Peek Column
£1,980.00
5190-2412 Agilent Bio MAb, NP5, 2.1 x 50mm, PK Guard Agilent Bio MAb 5 um 2.1 mm 50 mm Non-porous PEEK Guard
£973.00
5190-6885 Agilent Bio MAb, NP5, 21.2 x 250mm, SS Column Agilent Bio MAb 5 um 21.2 mm 250 mm Non-porous SS Column
£19,499.00
5190-2406 Agilent Bio MAb, NP5, 4 x 10mm, SS Guard Agilent Bio MAb 5 um 4.0 mm 10 mm Non-porous SS Guard
£551.00
5190-2407 Agilent Bio MAb, NP5, 4.6 x 250mm, PK Column Agilent Bio MAb 5 um 4.6 mm 250 mm Non-porous Peek Column
£1,817.00
5190-2405 Agilent Bio MAb, NP5, 4.6 x 250mm, SS Column Agilent Bio MAb 5 um 4.6 mm 250 mm Non-porous SS Column
£1,622.00
5190-2408 Agilent Bio MAb, NP5, 4.6 x 50mm, PK Guard Agilent Bio MAb 5 um 4.6 mm 50 mm Non-porous PEEK Guard
£973.00
  • A packing support composed of a rigid, spherical, highly cross-linked polystyrene divinylbenzene (PS/DVB) non-porous bead
  • Particles grafted with a hydrophilic, polymeric layer, virtually eliminating non-specific binding of antibody proteins
  • A different process is used to layer the weak cation-exchange phase to the particle making it a higher density than the Agilent Bio WCX column particles
  • Specifically designed for the separation of charge isoforms of monoclonal antibodies
  Agilent Bio MAb
Phase Weak cation exchange
Particle Type Non-porous
Particle Size 1.7, 3, 5 and 10 µm
pH Range 2 - 12
Maximum Temperature 80°C
Hardware Stainless Steel (1.7 µm, 3 µm, 5 µm, 10 µm)
PEEK (5 µm, 10 µm)
Bio MAb PEEK Columns Flyer (684.49 kB)
Robust, reproducible retention and resolution with Agilent Bio MAb PEEK columns
Charge Variant Analysis Application Compendium (10.49 MB)
Collection of Agilent app notes on charge variant analysis
Charge Variant Analysis Workflow Ordering Guide (568.81 kB)
mAb charge variant analysis by weak cation exchange (WCX) chromatography
Agilent Bio HPLC Columns (26.00 MB)

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