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Agilent Synthetic Chem Elut S SLE

Agilent Chem Elut S for supported liquid extraction (SLE) features an inert, synthetic sorbent and is ideal for biological, food, and environmental samples. Compared to traditional liquid-liquid extraction methodologies, SLE extraction reduces time and labour-intensive steps. In SLE, an aqueous sample is loaded onto a SLE cartridge or well and allowed time to adsorb to the surface of the solid support. Then, an immiscible organic solvent is passed over the inert material, eluting analytes of interest and leaving behind unwanted matrix like salts and polar interferences.

SLE cartridges differ from other cartridge-based extractions, like solid phase extraction (SPE), because the original sample is loaded onto the extraction bed and is not intended to flow through. Therefore, Agilent SLE cartridge and well plate formats are named according to the sample capacity, not bed mass. It is very important to choose the appropriate format based on your total loading sample volume.

For years, diatomaceous earth material has been used for SLE extractions. Since diatomaceous earth is mined, not manufactured, it is difficult to control particle size which can compromise results. Chem Elut S, a synthetic SLE extraction product, has a controlled particle size and delivers consistent flow and uniformity in every batch. This improves reproducibility by minimizing analyst-to-analyst and batch-to-batch variability.

Compared to time-consuming and labour-intensive liquid-liquid extraction, SLE extraction with Chem Elut S reduces analyst-to-analyst variability, improves matrix removal, and requires minimal extraction solvent, which leads to increased analyte concentration. Chem Elut delivers reliable, reproducible results with minimal method development and a walk-away workflow.

Part Number Short Description Pack Size Price Qty
5610-2008 Chem Elut S, 12mL Tube, 3mL Sample, 50pk 50
5610-2012 Chem Elut S, 1kg Bulk
5610-2005 Chem Elut S, 1mL Tube, 200uL Sample, 100pk 100
5610-2009 Chem Elut S, 20mL Tube, 5mL Sample, 50pk 50
5610-2003 Chem Elut S, 2mL 96 Well Plate, 200uL Sample, 1pk 1
5610-2004 Chem Elut S, 2mL 96 Well Plate, 400uL Sample, 1pk 1
5610-2006 Chem Elut S, 3mL Tube, 400uL Sample, 100pk 100
5610-2013 Chem Elut S, 4kg Bulk
5610-2010 Chem Elut S, 60mL Tube, 10mL Sample, 20pk 20
5610-2011 Chem Elut S, 60mL Tube, 20mL Sample, 20pk 20
5610-2007 Chem Elut S, 6mL Tube, 1mL Sample, 100pk 100
  • Improve reproducibility by minimizing analyst-to-analyst variability
  • Controlled particle and pore size enable consistent flow and reproducibility
  • Eliminate emulsions because shaking is removed
  • Achieve superior removal of matrix, including salts and phospholipids
  • Minimal extraction solvent required, leading to high analyte concentrations
Chem Elut S Flyer (644.01 kB)
Make the switch to Supported Liquid Extraction (SLE) for big productivity gains
Agilent Sample Preparation Portfolio Brochure (2.22 MB)
Outstanding analytical performance begins with the best sample preparation
Agilent Sample Preparation Catalogue (22.25 MB)
Consumable items for sample preparation from Agilent
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