Daicel Chiral Zwitterionic Chiral Columns

Daicel zwitterionic chiral columns CHIRALPAK ZWIX(+) and ZWIX(-) are packed with zwitterionic chiral stationary phases. These novel selectors incorporate both anion- and cation-exchange functional groups. They are designed for separation of zwitterionic molecules, such as underivatized amino acids and small peptides. The elution order of enantiomers can be systematically reversed on CHIRALPAK ZWIX(+) and CHIRALPAK ZWIX(-), although their column performance may not be exactly equal towards each analyte.

CHIRALPAK ZWIX(+) - quinine-derived (8S, 9R) chiral selector
CHIRALPAK ZWIX(-) - quinidine-derived (8R, 9S) chiral selector

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Part Number	Short Description	Phase	Particle Size	ID	Length	Type	Price
52334	CHIRALPAK ZWIX(-) 150 x 10mm 5um Semi-Prep Column	CHIRALPAK ZWIX(-)	5 um	10.0 mm	150 mm	Semi-Prep Column	£6,456.75
52344	CHIRALPAK ZWIX(-) 150 x 21mm 5um Semi-Prep Column	CHIRALPAK ZWIX(-)	5 um	21.0 mm	150 mm	Semi-Prep Column	£10,694.88
52584	CHIRALPAK ZWIX(-) 150 x 3mm 3um Analytical Column	CHIRALPAK ZWIX(-)	3 um	3.0 mm	150 mm	Analytical Column	£1,763.38
52514	CHIRALPAK ZWIX(-) 150 x 4mm 3um Analytical Column	CHIRALPAK ZWIX(-)	3 um	4.0 mm	150 mm	Analytical Column	£1,763.38
52335	CHIRALPAK ZWIX(-) 250 x 10mm 5um Semi-Prep Column	CHIRALPAK ZWIX(-)	5 um	10.0 mm	250 mm	Semi-Prep Column	£6,456.75
52345	CHIRALPAK ZWIX(-) 250 x 21mm 5um Semi-Prep Column	CHIRALPAK ZWIX(-)	5 um	21.0 mm	250 mm	Semi-Prep Column	£10,694.88
52585	CHIRALPAK ZWIX(-) 250 x 3mm 3um Analytical Column	CHIRALPAK ZWIX(-)	3 um	3.0 mm	250 mm	Analytical Column	£1,763.38
52515	CHIRALPAK ZWIX(-) 250 x 4mm 3um Analytical Column	CHIRALPAK ZWIX(-)	3 um	4.0 mm	250 mm	Analytical Column	£1,763.38
51334	CHIRALPAK ZWIX(+) 150 x 10mm 5um Semi-Prep Column	CHIRALPAK ZWIX(+)	5 um	10.0 mm	150 mm	Semi-Prep Column	£6,456.75
51344	CHIRALPAK ZWIX(+) 150 x 21mm 5um Semi-Prep Column	CHIRALPAK ZWIX(+)	5 um	21.0 mm	150 mm	Semi-Prep Column	£10,694.88
51584	CHIRALPAK ZWIX(+) 150 x 3mm 3um Analytical Column	CHIRALPAK ZWIX(+)	3 um	3.0 mm	150 mm	Analytical Column	£1,763.38
51514	CHIRALPAK ZWIX(+) 150 x 4mm 3um Analytical Column	CHIRALPAK ZWIX(+)	3 um	4.0 mm	150 mm	Analytical Column	£1,763.38
51335	CHIRALPAK ZWIX(+) 250 x 10mm 5um Semi-Prep Column	CHIRALPAK ZWIX(+)	5 um	10.0 mm	250 mm	Semi-Prep Column	£6,456.75
51345	CHIRALPAK ZWIX(+) 250 x 21mm 5um Semi-Prep Column	CHIRALPAK ZWIX(+)	5 um	21.0 mm	250 mm	Semi-Prep Column	£10,694.88
51585	CHIRALPAK ZWIX(+) 250 x 3mm 3um Analytical Column	CHIRALPAK ZWIX(+)	3 um	3.0 mm	150 mm	Analytical Column	£1,763.38
51515	CHIRALPAK ZWIX(+) 250 x 4mm 3um Analytical Column	CHIRALPAK ZWIX(+)	3 um	4.0 mm	250 mm	Analytical Column	£1,763.38

Features

Specialty phases for amino acids and zwitterionic compounds
Compatible with HPLC (polar organic phase and hydro-organic phase) and SFC applications
Compatible with all common HPLC solvents
Suitable for use in LC-MS detection

Specifications

	CHIRALPAK ZWIX(+)	CHIRALPAK ZWIX(-)
Chiral selector	quinine-derived (8S, 9R)	quinidine-derived (8R, 9S)
Particle size	3 and 5 µm	3 and 5 µm
Type	Immobilised	Immobilised
Separation mode	Polar organic phase and hydro-organic phase HPLC and SFC	Polar organic phase and hydro-organic phase HPLC and SFC
Shipping solvent	100% Methanol	100% Methanol
Temperature range	5 to 45°C	5 to 45°C

Literature

Daicel Chiral Selectors Poster (279.53 kB)

Structures of commercially available Daicel chiral stationary phases

Daicel Product List 2024 (2.97 MB)

Catalogue of part numbers for Daicel columns

CHIRALPAK ZWIX Screening Strategy (57.62 kB)

Screening strategies for zwitterionic columns to identify the best method to separate target compounds