Daicel Reversed Phase Coated Polysaccharide Chiral Columns

Reversed Phase Columns from Daicel

Reversed phase versions have been developed by Daicel specifically for aqueous-organic mobile phases. They are suited for applications where the sample is presented in aqueous media (e.g. biological samples) or for samples that require flexibility in term of pH range. These columns are also frequently used in LC-MS applications.

Reversed phase columns include:

CHIRALPAK AD
CHIRALPAK AS
CHIRALPAK AY
CHIRALPAK AZ
CHIRALCEL OD
CHIRALCEL OJ
CHIRALCEL OX
CHIRALCEL OZ

These have the same coated chiral selector as found in the normal phase stationary phases, however in comparison, they use a different bonded silica as the base material which stabilises the CSP.

Daicel reversed phase coated polysaccharide chiral columns have been developed specifically for aqueous-organic mobile phases. They are suited for applications where the sample is presented in aqueous media (e.g., biological samples) or for samples that require flexibility in term of pH range. These columns are also frequently used in LC-MS applications.

The reversed phase coated stationary phases have the same coated chiral selector as found in the normal phase stationary phases, however, they use a different bonded silica as the base material which stabilises the stationary phase.

Available reversed phase coated polysaccharide chiral columns are:
CHIRALPAK AD – amylose tris (3,5-dimethylphenylcarbamate) chiral selector
CHIRALPAK AS – amylose tris (S)-α-methylbenzylcarbamate chiral selector
CHIRALPAK AY – amylose tris (5-chloro-2-methylphenylcarbamate) chiral selector
CHIRALPAK AZ – amylose tris (3-chloro-4-methylphenylcarbamate) chiral selector
CHIRALCEL OD – cellulose tris (3,5-dimethylphenylcarbamate) chiral selector (USP L93)
CHIRALCEL OJ – cellulose tris (4-methylbenzoate) chiral selector (USP 107)
CHIRALCEL OX – cellulose tris (4-chloro-3-methylphenylcarbamate) chiral selector
CHIRALCEL OZ – cellulose tris (3-chloro-4-methylphenylcarbamate) chiral selector

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Buy

Part Number	Short Description	Phase	Particle Size	ID	Length	Type	Price
14811	CHIRALCEL OD-3R 10 x 4mm 3um Guard Cartridge, 3pk	CHIRALCEL OD	3 um	4.0 mm	10 mm	Guard	£360.26
14893	CHIRALCEL OD-3R 100 x 2.1mm 3um Analytical Column	CHIRALCEL OD	3 um	2.1 mm	100 mm	Analytical Column	£1,369.94
14823	CHIRALCEL OD-3R 100 x 4.6mm 3um Analytical Column	CHIRALCEL OD	3 um	4.6 mm	100 mm	Analytical Column	£1,369.94
14894	CHIRALCEL OD-3R 150 x 2.1mm 3um Analytical Column	CHIRALCEL OD	3 um	2.1 mm	150 mm	Analytical Column	£1,734.94
14824	CHIRALCEL OD-3R 150 x 4.6mm 3um Analytical Column	CHIRALCEL OD	3 um	4.6 mm	150 mm	Analytical Column	£1,734.94
14895	CHIRALCEL OD-3R 250 x 2.1mm 3um Analytical Column	CHIRALCEL OD	3 um	2.1 mm	250 mm	Analytical Column	£1,734.94
14892	CHIRALCEL OD-3R 50 x 2.1mm 3um Analytical Column	CHIRALCEL OD	3 um	2.1 mm	50 mm	Analytical Column	£1,004.94
14822	CHIRALCEL OD-3R 50 x 4.6mm 3um Analytical Column	CHIRALCEL OD	3 um	4.6 mm	50 mm	Analytical Column	£1,004.94
14611	CHIRALCEL OD-R 10 x 4mm 10um Guard Cartridge, 3pk	CHIRALCEL OD	10 um	4.0 mm	10 mm	Guard	£360.26
14625	CHIRALCEL OD-R 250 x 4.6mm 10um Analytical Column	CHIRALCEL OD	10 um	4.6 mm	250 mm	Analytical Column	£1,734.94
14711	CHIRALCEL OD-RH 10 x 4mm 5um Guard Cartridge, 3pk	CHIRALCEL OD	5 um	4.0 mm	10 mm	Guard	£360.26
14794	CHIRALCEL OD-RH 150 x 2.1mm 5um Analytical Column	CHIRALCEL OD	5 um	2.1 mm	150 mm	Analytical Column	£1,734.94
14724	CHIRALCEL OD-RH 150 x 4.6mm 5um Analytical Column	CHIRALCEL OD	5 um	4.6 mm	150 mm	Analytical Column	£1,734.94
17811	CHIRALCEL OJ-3R 10 x 4mm 3um Guard Cartridge, 3pk	CHIRALCEL OJ	3 um	4.0 mm	10 mm	Guard	£360.26
17893	CHIRALCEL OJ-3R 100 x 2.1mm 3um Analytical Column	CHIRALCEL OJ	3 um	2.1 mm	100 mm	Analytical Column	£1,369.94
17823	CHIRALCEL OJ-3R 100 x 4.6mm 3um Analytical Column	CHIRALCEL OJ	3 um	4.6 mm	100 mm	Analytical Column	£1,369.94
17894	CHIRALCEL OJ-3R 150 x 2.1mm 3um Analytical Column	CHIRALCEL OJ	3 um	2.1 mm	150 mm	Analytical Column	£1,734.94
17824	CHIRALCEL OJ-3R 150 x 4.6mm 3um Analytical Column	CHIRALCEL OJ	3 um	4.6 mm	150 mm	Analytical Column	£1,734.94
17895	CHIRALCEL OJ-3R 250 x 2.1mm 3um Analytical Column	CHIRALCEL OJ	3 um	2.1 mm	250 mm	Analytical Column	£1,734.94
17892	CHIRALCEL OJ-3R 50 x 2.1mm 3um Analytical Column	CHIRALCEL OJ	3 um	2.1 mm	50 mm	Analytical Column	£1,004.94
17822	CHIRALCEL OJ-3R 50 x 4.6mm 3um Analytical Column	CHIRALCEL OJ	3 um	4.6 mm	50 mm	Analytical Column	£1,004.94
17711	CHIRALCEL OJ-RH 10 x 4mm 5um Guard Cartridge, 3pk	CHIRALCEL OJ	5 um	4.0 mm	10 mm	Guard	£360.26
17794	CHIRALCEL OJ-RH 150 x 2.1mm 5um Analytical Column	CHIRALCEL OJ	5 um	2.1 mm	150 mm	Analytical Column	£1,734.94
17724	CHIRALCEL OJ-RH 150 x 4.6mm 5um Analytical Column	CHIRALCEL OJ	5 um	4.6 mm	150 mm	Analytical Column	£1,734.94
63811	CHIRALCEL OX-3R 10 x 4mm 3um Guard Cartridge, 3pk	CHIRALCEL OX	3 um	4.0 mm	10 mm	Guard	£360.26
63893	CHIRALCEL OX-3R 100 x 2.1mm 3um Analytical Column	CHIRALCEL OX	3 um	2.1 mm	100 mm	Analytical Column	£1,369.94
63823	CHIRALCEL OX-3R 100 x 4.6mm 3um Analytical Column	CHIRALCEL OX	3 um	4.6 mm	100 mm	Analytical Column	£1,369.94
63894	CHIRALCEL OX-3R 150 x 2.1mm 3um Analytical Column	CHIRALCEL OX	3 um	2.1 mm	150 mm	Analytical Column	£1,734.94
63824	CHIRALCEL OX-3R 150 x 4.6mm 3um Analytical Column	CHIRALCEL OX	3 um	4.6 mm	150 mm	Analytical Column	£1,734.94
63895	CHIRALCEL OX-3R 250 x 2.1mm 5um Analytical Column	CHIRALCEL OX	3 um	2.1 mm	250 mm	Analytical Column	£1,734.94
63892	CHIRALCEL OX-3R 50 x 2.1mm 3um Analytical Column	CHIRALCEL OX	3 um	2.1 mm	50 mm	Analytical Column	£1,004.94
63822	CHIRALCEL OX-3R 50 x 4.6mm 3um Analytical Column	CHIRALCEL OX	3 um	4.6 mm	50 mm	Analytical Column	£1,004.94
63711	CHIRALCEL OX-RH 10 x 4mm 5um Guard Cartridge, 3pk	CHIRALCEL OX	5 um	4.0 mm	10 mm	Guard	£360.26
63794	CHIRALCEL OX-RH 150 x 2.1mm 5um Analytical Column	CHIRALCEL OX	5 um	2.1 mm	150 mm	Analytical Column	£1,734.94
63724	CHIRALCEL OX-RH 150 x 4.6mm 5um Analytical Column	CHIRALCEL OX	5 um	4.6 mm	150 mm	Analytical Column	£1,734.94
42811	CHIRALCEL OZ-3R 10 x 4mm 3um Guard Cartridge, 3pk	CHIRALCEL OZ	3 um	4.0 mm	10 mm	Guard	£360.26
42893	CHIRALCEL OZ-3R 100 x 2.1mm 3um Analytical Column	CHIRALCEL OZ	3 um	2.1 mm	100 mm	Analytical Column	£1,369.94
42823	CHIRALCEL OZ-3R 100 x 4.6mm 3um Analytical Column	CHIRALCEL OZ	3 um	4.6 mm	100 mm	Analytical Column	£1,369.94
42894	CHIRALCEL OZ-3R 150 x 2.1mm 3um Analytical Column	CHIRALCEL OZ	3 um	2.1 mm	150 mm	Analytical Column	£1,734.94
42824	CHIRALCEL OZ-3R 150 x 4.6mm 3um Analytical Column	CHIRALCEL OZ	3 um	4.6 mm	150 mm	Analytical Column	£1,734.94
42895	CHIRALCEL OZ-3R 250 x 2.1mm 3um Analytical Column	CHIRALCEL OZ	3 um	2.1 mm	250 mm	Analytical Column	£1,734.94
42892	CHIRALCEL OZ-3R 50 x 2.1mm 3um Analytical Column	CHIRALCEL OZ	3 um	2.1 mm	50 mm	Analytical Column	£1,004.94
42822	CHIRALCEL OZ-3R 50 x 4.6mm 3um Analytical Column	CHIRALCEL OZ	3 um	4.6 mm	50 mm	Analytical Column	£1,004.94
42711	CHIRALCEL OZ-RH 10 x 4mm 5um Guard Cartridge, 3pk	CHIRALCEL OZ	5 um	4.0 mm	10 mm	Guard	£360.26
42794	CHIRALCEL OZ-RH 150 x 2.1mm 5um Analytical Column	CHIRALCEL OZ	5 um	2.1 mm	150 mm	Analytical Column	£1,734.94
42724	CHIRALCEL OZ-RH 150 x 4.6mm 5um Analytical Column	CHIRALCEL OZ	5 um	4.6 mm	150 mm	Analytical Column	£1,734.94
19811	CHIRALPAK AD-3R 10 x 4mm 3um Guard Cartridge, 3pk	CHIRALPAK AD	3 um	4.0 mm	10 mm	Guard	£360.26
19893	CHIRALPAK AD-3R 100 x 2.1mm 3um Analytical Column	CHIRALPAK AD	3 um	2.1 mm	100 mm	Analytical Column	£1,369.94
19823	CHIRALPAK AD-3R 100 x 4.6mm 3um Analytical Column	CHIRALPAK AD	3 um	4.6 mm	100 mm	Analytical Column	£1,369.94
19894	CHIRALPAK AD-3R 150 x 2.1mm 3um Analytical Column	CHIRALPAK AD	3 um	2.1 mm	150 mm	Analytical Column	£1,734.94
19824	CHIRALPAK AD-3R 150 x 4.6mm 3um Analytical Column	CHIRALPAK AD	3 um	4.6 mm	150 mm	Analytical Column	£1,734.94
19895	CHIRALPAK AD-3R 250 x 2.1mm 3um Analytical Column	CHIRALPAK AD	3 um	2.1 mm	250 mm	Analytical Column	£1,734.94
19892	CHIRALPAK AD-3R 50 x 2.1mm 3um Analytical Column	CHIRALPAK AD	3 um	2.1 mm	50 mm	Analytical Column	£1,004.94
19822	CHIRALPAK AD-3R 50 x 4.6mm 3um Analytical Column	CHIRALPAK AD	3 um	4.6 mm	50 mm	Analytical Column	£1,004.94
19711	CHIRALPAK AD-RH 10 x 4mm 5um Guard Cartridge, 3pk	CHIRALPAK AD	5 um	4.0 mm	10 mm	Guard	£360.26
19794	CHIRALPAK AD-RH 150 x 2.1mm 5um Analytical Column	CHIRALPAK AD	5 um	2.1 mm	150 mm	Analytical Column	£1,734.94
19724	CHIRALPAK AD-RH 150 x 4.6mm 5um Analytical Column	CHIRALPAK AD	5 um	4.6 mm	150 mm	Analytical Column	£1,734.94
20811	CHIRALPAK AS-3R 10 x 4mm 3um Guard Cartridge, 3pk	CHIRALPAK AS	3 um	4.0 mm	10 mm	Guard	£360.26
20893	CHIRALPAK AS-3R 100 x 2.1mm 3um Analytical Column	CHIRALPAK AS	3 um	2.1 mm	100 mm	Analytical Column	£1,369.94
20823	CHIRALPAK AS-3R 100 x 4.6mm 3um Analytical Column	CHIRALPAK AS	3 um	4.6 mm	100 mm	Analytical Column	£1,369.94
20894	CHIRALPAK AS-3R 150 x 2.1mm 3um Analytical Column	CHIRALPAK AS	3 um	2.1 mm	150 mm	Analytical Column	£1,734.94
20824	CHIRALPAK AS-3R 150 x 4.6mm 3um Analytical Column	CHIRALPAK AS	3 um	4.6 mm	150 mm	Analytical Column	£1,734.94
20895	CHIRALPAK AS-3R 250 x 2.1mm 3um Analytical Column	CHIRALPAK AS	3 um	2.1 mm	250 mm	Analytical Column	£1,734.94
20892	CHIRALPAK AS-3R 50 x 2.1mm 3um Analytical Column	CHIRALPAK AS	3 um	2.1 mm	50 mm	Analytical Column	£1,004.94
20822	CHIRALPAK AS-3R 50 x 4.6mm 3um Analytical Column	CHIRALPAK AS	3 um	4.6 mm	50 mm	Analytical Column	£1,004.94
20711	CHIRALPAK AS-RH 10 x 4mm 5um Guard Cartridge, 3pk	CHIRALPAK AS	5 um	4.0 mm	10 mm	Guard	£360.26
20794	CHIRALPAK AS-RH 150 x 2.1mm 5um Analytical Column	CHIRALPAK AS	5 um	2.1 mm	150 mm	Analytical Column	£1,734.94
20724	CHIRALPAK AS-RH 150 x 4.6mm 5um Analytical Column	CHIRALPAK AS	5 um	4.6 mm	150 mm	Analytical Column	£1,734.94
47811	CHIRALPAK AY-3R 10 x 4mm 3um Guard Cartridge, 3pk	CHIRALPAK AY	3 um	4.0 mm	10 mm	Guard	£360.26
47893	CHIRALPAK AY-3R 100 x 2.1mm 3um Analytical Column	CHIRALPAK AY	3 um	2.1 mm	100 mm	Analytical Column	£1,369.94
47823	CHIRALPAK AY-3R 100 x 4.6mm 3um Analytical Column	CHIRALPAK AY	3 um	4.6 mm	100 mm	Analytical Column	£1,369.94
47894	CHIRALPAK AY-3R 150 x 2.1mm 3um Analytical Column	CHIRALPAK AY	3 um	2.1 mm	150 mm	Analytical Column	£1,734.94
47824	CHIRALPAK AY-3R 150 x 4.6mm 3um Analytical Column	CHIRALPAK AY	3 um	4.6 mm	150 mm	Analytical Column	£1,734.94
47895	CHIRALPAK AY-3R 250 x 2.1mm 3um Analytical Column	CHIRALPAK AY	3 um	2.1 mm	250 mm	Analytical Column	£1,734.94
47892	CHIRALPAK AY-3R 50 x 2.1mm 3um Analytical Column	CHIRALPAK AY	3 um	2.1 mm	50 mm	Analytical Column	£1,004.94
47822	CHIRALPAK AY-3R 50 x 4.6mm 3um Analytical Column	CHIRALPAK AY	3 um	4.6 mm	50 mm	Analytical Column	£1,004.94
47711	CHIRALPAK AY-RH 10 x 4mm 5um Guard Cartridge, 3pk	CHIRALPAK AY	5 um	4.0 mm	10 mm	Guard	£360.26
47794	CHIRALPAK AY-RH 150 x 2.1mm 5um Analytical Column	CHIRALPAK AY	5 um	2.1 mm	150 mm	Analytical Column	£1,734.94
47724	CHIRALPAK AY-RH 150 x 4.6mm 5um Analytical Column	CHIRALPAK AY	5 um	4.6 mm	150 mm	Analytical Column	£1,734.94
61811	CHIRALPAK AZ-3R 10 x 4mm 3um Guard Cartridge, 3pk	CHIRALPAK AZ	3 um	4.0 mm	10 mm	Guard	£360.26
61893	CHIRALPAK AZ-3R 100 x 2.1mm 3um Analytical Column	CHIRALPAK AZ	3 um	2.1 mm	100 mm	Analytical Column	£1,369.94
61823	CHIRALPAK AZ-3R 100 x 4.6mm 3um Analytical Column	CHIRALPAK AZ	3 um	4.6 mm	100 mm	Analytical Column	£1,369.94
61894	CHIRALPAK AZ-3R 150 x 2.1mm 3um Analytical Column	CHIRALPAK AZ	3 um	2.1 mm	150 mm	Analytical Column	£1,734.94
61824	CHIRALPAK AZ-3R 150 x 4.6mm 3um Analytical Column	CHIRALPAK AZ	3 um	4.6 mm	150 mm	Analytical Column	£1,734.94
61895	CHIRALPAK AZ-3R 250 x 2.1mm 3um Analytical Column	CHIRALPAK AZ	3 um	2.1 mm	250 mm	Analytical Column	£1,734.94
61892	CHIRALPAK AZ-3R 50 x 2.1mm 3um Analytical Column	CHIRALPAK AZ	3 um	2.1 mm	50 mm	Analytical Column	£1,004.94
61822	CHIRALPAK AZ-3R 50 x 4.6mm 3um Analytical Column	CHIRALPAK AZ	3 um	4.6 mm	50 mm	Analytical Column	£1,004.94
61711	CHIRALPAK AZ-RH 10 x 4mm 5um Guard Cartridge, 3pk	CHIRALPAK AZ	5 um	4.0 mm	10 mm	Guard	£360.26
61794	CHIRALPAK AZ-RH 150 x 2.1mm 5um Analytical Column	CHIRALPAK AZ	5 um	2.1 mm	150 mm	Analytical Column	£1,734.94
61724	CHIRALPAK AZ-RH 150 x 4.6mm 5um Analytical Column	CHIRALPAK AZ	5 um	4.6 mm	150 mm	Analytical Column	£1,734.94

Features

For reverse phase use with aqueous/organic mobile phases
Traditional 10 µm, high resolution 5 µm and ultra-fast 3 µm particle sizes
Suitable for bioanalytical applications and drug product chiral analysis
LC-MS/MS compatible
pH range 2 to 9
Comprehensive screening strategies available for carrying out custom method development in-house

Specifications

	CHIRALPAK AD	CHIRALPAK AS	CHIRALPAK AY	CHIRALPAK AZ	CHIRALCEL OD	CHIRALCEL OJ	CHIRALCEL OX	CHIRALCEL OZ
Chiral selector	amylose tris (3,5-dimethylphenylcarbamate)	amylose tris (S)-α-methylbenzylcarbamate	amylose tris (5-chloro-2-methylphenylcarbamate)	amylose tris (3-chloro-4-methylphenylcarbamate)	cellulose tris (3,5-dimethylphenylcarbamate)	cellulose tris (4-methylbenzoate)	cellulose tris (4-chloro-3-methylphenylcarbamate)	cellulose tris (3-chloro-4-methylphenylcarbamate)
USP	-	-	-	-	USP L93	USP 107	-	-
Particle size	3, 5 µm	3, 5 µm	3, 5 µm	3, 5 µm	3, 5, 10 µm	3, 5 µm	3, 5 µm	3, 5 µm
Type	Coated	Coated	Coated	Coated	Coated	Coated	Coated	Coated
Separation mode	reversed phase	reversed phase	reversed phase	reversed phase	reversed phase	reversed phase	reversed phase	reversed phase
Shipping solvent	Water/Acetonitrile (60/40)	Water/Acetonitrile (60/40)	Water/Acetonitrile (60/40)	Water/Acetonitrile (60/40)	Water/Acetonitrile (60/40)	Water/Acetonitrile (60/40)	Water/Acetonitrile (60/40)	Water/Acetonitrile (60/40)
Temperature range	0 - 40°C	0 - 40°C	0 - 40°C	0 - 40°C	0 - 40°C	0 - 40°C	0 - 40°C	0 - 40°C

Literature

Daicel Chiral Selectors Poster (279.53 kB)

Structures of commercially available Daicel chiral stationary phases

Daicel Product List 2024 (2.97 MB)

Catalogue of part numbers for Daicel columns

Coated Polysaccharides Screening Strategy (74.54 kB)

Screening strategies for coated chiral stationary phases to enable the identification of the best method to separate target compounds