Thermo Scientific MAbPac RP Columns

The Thermo Scientific MAbPac RP columns are designed for comprehensive characterization of mAb purity by reversed-phase liquid chromatography. High resolution of intact mAb, mAb fragments such as light chain (LC), heavy chain (HC), Fc and Fab, scFc and F(ab’)2, will reveal the location, as well as nature, of modification using LC/UV or LC/MS.

The MAbPac RP column is a reversed-phase (RP) column based on a macroporous resin specifically designed for high resolution separation of intact monoclonal antibodies (mAbs) and mAb fragments. The stationary phase is fully compatible with mass spectrometry friendly organic solvents such as acetonitrile and isopropanol, as well as low pH eluents containing trifluoroacetic acid or formic acid.

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Part Number	Short Description	Phase	Particle Size	ID	Length	Pore Size	Type	Price
088644	MAbPac RP, 4um, 3 x 100mm, Column	MAbPac RP	4 um	3.0 mm	100 mm	300 A	Column	£653.15
088645	MAbPac RP, 4um, 3 x 50mm, Column	MAbPac RP	4 um	3.0 mm	50 mm	300 A	Column	£558.67
088646	MAbPac RP, 4um, 3 x 10mm, Guard Cartridge, 2pk	MAbPac RP	4 um	3.0 mm	10 mm	300 A	Guard	£160.96
088647	MAbPac RP, 4um, 2.1 x 100mm, Column	MAbPac RP	4 um	2.1 mm	100 mm	300 A	Column	£653.15
088648	MAbPac RP, 4um, 2.1 x 50mm, Column	MAbPac RP	4 um	2.1 mm	50 mm	300 A	Column	£558.67
088649	MAbPac RP, 4um, 2.1 x 10mm, Guard Cartridge, 2pk	MAbPac RP	4 um	2.1 mm	10 mm	300 A	Guard	£160.96
303182	MAbPac RP, 4um, 1 x 50mm, Column	MAbPac RP	4 um	1.0 mm	50 mm	300 A	Column	£840.93
303269	MAbPac RP, 4um, 3 x 150mm, Column	MAbPac RP	4 um	3.0 mm	150 mm	300 A	Column	£884.08
303270	MAbPac RP, 4um, 2.1 x 150mm, Column	MAbPac RP	4 um	2.1 mm	150 mm	300 A	Column	£845.59

Features

Resin is based on a hydrophobic supermacroporous 4µm polymer particles
Designed for reversed-phase biomolecule LC and LC/MS separations
Superior resolution power for monoclonal antibodies and related substances
High efficiency with low carry-over
Excellent MS compatibility
Wide operating pH range of 0 to 14
High temperature stability up to 110°C
Fast separations capability for high throughput separations

Specifications

	MAbPac RP
Phase	Phenyl
Particle Type	DVB (Divinylbenzene) Polymer
Particle Size	4 µm
Pore Size	1500 Å
pH Range	0 – 14
Maximum Temperature	110°C
Hardware	Stainless Steel
Pressure Limit	275 bar