Thermo Scientific Acclaim HILIC-10 HPLC Columns
Separate highly hydrophilic molecules by hydrophilic interaction liquid chromatography using Thermo Scientific Acclaim HILIC-10 LC Columns.
These columns retain and separate highly polar molecules that are unretained by reversed-phase chromatography. Their high-purity, spherical, porous silica base is covalently modified with a proprietary hydrophilic layer. This chemistry enables the use of 5–20% aqueous mobile phase while maintaining affinity for polar analytes.
Sample throughput is increased without the need to evaporate and reconstitute samples dissolved in nonaqueous solvents.
The Thermo Scientific Acclaim HILIC-10 column is designed for separating highly hydrophilic molecules by Hydrophilic Interaction Liquid Chromatography (HILIC). This column is based on high-purity spherical porous silica covalently modified with a proprietary hydrophilic layer. This chemistry enables the use of 5 – 20% aqueous mobile phase while maintaining affinity for polar analytes.
- Designed with unique selectivity for hydrophilic molecules
- Retains highly polar molecules that are not retained by reversed phase chromatography
- Enhanced sensitivity for MS detection
- Hydrolytically stable
- Rugged column packing
- Broad application range, including separation of hydrophilic drugs and drug metabolites
| Acclaim HILIC-10 | |
| Bonded Phase | Proprietary Polar Group |
| Particle Type | Fully Porous |
| Particle Size | 3 µm |
| Pore Size | 120 Å |
| Surface Area | 300 m2/g |
| Carbon Load | 8% |
| pH Range | 2 - 8 |
| Temperature Range | 70°C |
| Hardware | Stainless steel |
Thermo Scientific HILIC Separations Guide
(14.08 MB)
LC Columns Technical Guide
(13.60 MB)
Analytical UHPLC and HPLC Columns Brochure
(11.02 MB)
Thermo LC Columns and Accessories Catalogue 2022-2023
(8.87 MB)