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Thermo Scientific Syncronis HILIC HPLC Columns

Thermo Scientific Syncronis HILIC HPLC columns ensure consistent and predictable separations of polar and hydrophilic analytes. Highly pure, high surface area silica and dense stationary phase coverage minimises secondary interactions and provides reproducible high-resolution separations. The zwitterionic stationary phase results in a neutral, highly polar surface and provides alternative selectivity to C18 columns without ion-pairing or derivatization. The highly organic mobile phases used with Syncronis HILIC columns increases desolvation efficiency in MS detection.

Part Number Short Description Phase Type Phase Particle Size ID Length Pore Size Type Price Qty
97502-052130 Syncronis HILIC, 1.7um, 50 x 2.1mm, Column Zwitterionic Syncronis HILIC 1.7 um 2.1 mm 50 mm 100 A Column
£730.33
97502-102130 Syncronis HILIC, 1.7um, 100 x 2.1mm, Column Zwitterionic Syncronis HILIC 1.7 um 2.1 mm 100 mm 100 A Column
£730.33
97503-052130 Syncronis HILIC, 3um, 50 x 2.1mm, Column Zwitterionic Syncronis HILIC 3 um 2.1 mm 50 mm 100 A Column
£642.26
97503-104630 Syncronis HILIC, 3um, 100 x 4.6mm, Column Zwitterionic Syncronis HILIC 3 um 4.6 mm 100 mm 100 A Column
£665.75
97503-154630 Syncronis HILIC, 3um, 150 x 4.6mm, Column Zwitterionic Syncronis HILIC 3 um 4.6 mm 150 mm 100 A Column
£784.29
97505-012101 Syncronis HILIC, 5um, 10 x 2.1mm, Drop-in Guard, 4pk Zwitterionic Syncronis HILIC 5 um 2.1 mm 10 mm 100 A Guard
£333.57
97505-014001 Syncronis HILIC, 5um, 10 x 4mm, Drop-in Guard, 4pk Zwitterionic Syncronis HILIC 5 um 4/4.6 mm 10 mm 100 A Guard
£333.57
97505-052130 Syncronis HILIC, 5um, 50 x 2.1mm, Column Zwitterionic Syncronis HILIC 5 um 2.1 mm 50 mm 100 A Column
£578.50
97505-102130 Syncronis HILIC, 5um, 100 x 2.1mm, Column Zwitterionic Syncronis HILIC 5 um 2.1 mm 100 mm 100 A Column
£634.49
97505-152130 Syncronis HILIC, 5um, 150 x 2.1mm, Column Zwitterionic Syncronis HILIC 5 um 2.1 mm 150 mm 100 A Column
£669.48
97505-153030 Syncronis HILIC, 5um, 150 x 3mm, Column Zwitterionic Syncronis HILIC 5 um 3.0 mm 150 mm 100 A Column
£669.48
97505-154630 Syncronis HILIC, 5um, 150 x 4.6mm, Column Zwitterionic Syncronis HILIC 5 um 4.6 mm 150 mm 100 A Column
£647.59
97505-254630 Syncronis HILIC, 5um, 250 x 4.6mm, Column Zwitterionic Syncronis HILIC 5 um 4.6 mm 250 mm 100 A Column
£692.69
  • Provides enhanced retention of polar and hydrophilic analytes
  • Sulfobetaine zwitterion has both positive (quaternary ammonium) and negative (sulfonic acid) groups in a 1:1 ratio, so the net charge is zero
  • Dense surface coverage of silica minimizes secondary interactions and peak tailing
  • Highly pure, high surface area silica particles
  • Outstanding peak shape and sensitivity
  • Manufactured, packed and tested in ISO-9000-accredited facilities
  • 1.7 µm for rapid UHPLC separations, 3 µm and 5 µm for traditional HPLC analysis
  Syncronis HILIC
Bonded Phase Zwitterionic
Particle Type Fully Porous
Particle Size 1.7 µm, 3 µm, 5 µm
Pore Size 100 Å
Surface Area 320 m2/g
Endcapped No
Carbon Load 5%
Maximum Temperature 60°C
pH Range 2 - 8
Pressure Limit 3 µm and 5 µm - 400 bar
1.7 µm - 1250 bar
Hardware Stainless Steel
Syncronis HILIC Product Specifications (529.35 kB)
Enhanced retention of polar and hydrophilic analytes using Thermo Scientific Syncronis HILIC columns
Syncronis Technical Guide (9.38 MB)
Remarkable separations guaranteed time after time
Thermo Scientific HILIC Separations Guide (14.08 MB)
Practical guide to HILIC mechanisms, method development and troubleshooting
Thermo LC Columns and Accessories Catalogue 2022-2023 (8.87 MB)
Latest and most comprehensive range of innovative columns, accessories and equipment for fast LC, analytical HPLC and UHPLC
LC Columns Technical Guide (13.60 MB)
Selection charts based on stationary phase use, analyte properties, LC-MS requirements or USP specifications
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