SiELC Newcrom A HPLC Columns

SiELC Newcrom A is a mixed-mode HPLC column with negatively charged acidic ion-pairing groups at the terminal end of long ligand chains. This new generation of mixed-mode column moves the charged embedded functional group away from the silica surface enabling uniform surface charge density. Limitations such as restricted use of methanol in the mobile phase, poor peak shape, low efficiency of multi-charged molecules, high buffer concentration requirement and poor retention of non-charged molecules have been overcome with the Newcrom stationary phases.

Newcrom A is based on spherical silica particles with 100 Å pores and particle sizes of 3 µm and 5 µm. It has a longer ligand chain (100 Å) compared to Newcrom AH (25 Å). The longer ligand chains reduce the number of ionic groups over any given surface area, so Newcrom A has a lower ion capacity compared to Newcrom AH.

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Part Number	Short Description	Phase	Particle Size	ID	Length	Pore Size	Type	Price
NA-21.025.0510	Newcrom A Column 2.1 x 25mm 5um 100A	Newcrom A	5 um	2.1 mm	25 mm	100 A	Column	£980.18
NA-21.025.0310	Newcrom A Column 2.1 x 25mm 3um 100A	Newcrom A	3 um	2.1 mm	25 mm	100 A	Column	£980.18
NA-21.050.0510	Newcrom A Column 2.1 x 50mm 5um 100A	Newcrom A	5 um	2.1 mm	50 mm	100 A	Column	£1,096.57
NA-21.050.0310	Newcrom A Column 2.1 x 50mm 3um 100A	Newcrom A	3 um	2.1 mm	50 mm	100 A	Column	£1,200.72
NA-21.100.0310	Newcrom A Column 2.1 x 100mm 3um 100A	Newcrom A	3 um	2.1 mm	100 mm	100 A	Column	£1,231.35
NA-21.100.0510	Newcrom A Column 2.1 x 100mm 5um 100A	Newcrom A	5 um	2.1 mm	100 mm	100 A	Column	£1,133.34
NA-21.150.0310	Newcrom A Column 2.1 x 150mm 3um 100A	Newcrom A	3 um	2.1 mm	150 mm	100 A	Column	£1,261.96
NA-21.150.0510	Newcrom A Column 2.1 x 150mm 5um 100A	Newcrom A	5 um	2.1 mm	150 mm	100 A	Column	£1,151.71
NA-21.250.0510	Newcrom A Column 2.1 x 250mm 5um 100A	Newcrom A	5 um	2.1 mm	250 mm	100 A	Column	£1,200.72
NA-21.G.0310	Newcrom A Guard Column 2.1 x 10mm 3um 100A, 2pk	Newcrom A	3 um	2.1 mm	10 mm	100 A	Guard	£441.08
NA-21.G.0510	Newcrom A Guard Column 2.1 x 10mm 5um 100A, 2pk	Newcrom A	5 um	2.1 mm	10 mm	100 A	Guard	£416.57
NA-220.050.0510	Newcrom A Column 22 x 50mm 5um 100A	Newcrom A	5 um	22.0 mm	50 mm	100 A	Column	£5,091.33
NA-220.100.0510	Newcrom A Column 22 x 100mm 5um 100A	Newcrom A	5 um	22.0 mm	100 mm	100 A	Column	£5,847.47
NA-220.150.0510	Newcrom A Column 22 x 150mm 5um 100A	Newcrom A	5 um	22.0 mm	150 mm	100 A	Column	£7,275.73
NA-220.250.0510	Newcrom A Column 22 x 250mm 5um 100A	Newcrom A	5 um	22.0 mm	250 mm	100 A	Column	£9,157.67
NA-32.025.0310	Newcrom A Column 3.2 x 25mm 3um 100A	Newcrom A	3 um	3.2 mm	25 mm	100 A	Column	£980.18
NA-32.025.0510	Newcrom A Column 3.2 x 25mm 5um 100A	Newcrom A	5 um	3.2 mm	25 mm	100 A	Column	£980.18
NA-32.050.0310	Newcrom A Column 3.2 x 50mm 3um 100A	Newcrom A	3 um	3.2 mm	50 mm	100 A	Column	£1,200.72
NA-32.050.0510	Newcrom A Column 3.2 x 50mm 5um 100A	Newcrom A	5 um	3.2 mm	50 mm	100 A	Column	£1,096.57
NA-32.100.0310	Newcrom A Column 3.2 x 100mm 3um 100A	Newcrom A	3 um	3.2 mm	100 mm	100 A	Column	£1,225.22
NA-32.100.0510	Newcrom A Column 3.2 x 100mm 5um 100A	Newcrom A	5 um	3.2 mm	100 mm	100 A	Column	£1,133.34
NA-32.150.0310	Newcrom A Column 3.2 x 150mm 3um 100A	Newcrom A	3 um	3.2 mm	150 mm	100 A	Column	£1,286.46
NA-32.150.0510	Newcrom A Column 3.2 x 150mm 5um 100A	Newcrom A	5 um	3.2 mm	150 mm	100 A	Column	£1,176.20
NA-32.250.0510	Newcrom A Column 3.2 x 250mm 5um 100A	Newcrom A	5 um	3.2 mm	250 mm	100 A	Column	£1,237.47
NA-32.G.0310	Newcrom A Guard Column 3.2 x 10mm 3um 100A, 2pk	Newcrom A	3 um	3.2 mm	10 mm	100 A	Guard	£441.08
NA-32.G.0510	Newcrom A Guard Column 3.2 x 10mm 5um 100A, 2pk	Newcrom A	5 um	3.2 mm	10 mm	100 A	Guard	£416.57
NA-46.050.0310	Newcrom A Column 4.6 x 50mm 3um 100A	Newcrom A	3 um	4.6 mm	50 mm	100 A	Column	£1,133.34
NA-46.050.0510	Newcrom A Column 4.6 x 50mm 5um 100A	Newcrom A	5 um	4.6 mm	50 mm	100 A	Column	£1,029.19
NA-46.100.0310	Newcrom A Column 4.6 x 100mm 3um 100A	Newcrom A	3 um	4.6 mm	100 mm	100 A	Column	£1,029.19
NA-46.100.0510	Newcrom A Column 4.6 x 100mm 5um 100A	Newcrom A	5 um	4.6 mm	100 mm	100 A	Column	£1,133.34
NA-46.150.0310	Newcrom A Column 4.6 x 150mm 3um 100A	Newcrom A	3 um	4.6 mm	150 mm	100 A	Column	£1,286.46
NA-46.150.0510	Newcrom A Column 4.6 x 150mm 5um 100A	Newcrom A	5 um	4.6 mm	150 mm	100 A	Column	£1,170.08
NA-46.250.0510	Newcrom A Column 4.6 x 250mm 5um 100A	Newcrom A	5 um	4.6 mm	250 mm	100 A	Column	£1,280.36
NA-46.G.0310	Newcrom A Guard Column 4.6 x 10mm 3um 100A, 2pk	Newcrom A	3 um	4.6 mm	10 mm	100 A	Guard	£441.08
NA-46.G.0510	Newcrom A Guard Column 4.6 x 10mm 5um 100A, 2pk	Newcrom A	5 um	4.6 mm	10 mm	100 A	Guard	£416.57
NA-05.050.0310	Newcrom A Column 0.5 x 50mm 3um 100A	Newcrom A	3 um	0.5 mm	50 mm	100 A	Column	£1,118.44
NA-05.050.0510	Newcrom A Column 0.5 x 50mm 5um 100A	Newcrom A	5 um	0.5 mm	50 mm	100 A	Column	£1,118.44
NA-05.100.0310	Newcrom A Column 0.5 x 100mm 3um 100A	Newcrom A	3 um	0.5 mm	100 mm	100 A	Column	£1,128.43
NA-05.100.0510	Newcrom A Column 0.5 x 100mm 5um 100A	Newcrom A	5 um	0.5 mm	100 mm	100 A	Column	£1,128.43
NA-05.150.0510	Newcrom A Column 0.5 x 150mm 5um 100A	Newcrom A	5 um	0.5 mm	150 mm	100 A	Column	£1,118.44
NA-05.250.0310	Newcrom A Column 0.5 x 250mm 3um 100A	Newcrom A	3 um	0.5 mm	250 mm	100 A	Column	£1,088.48
NA-05.250.0510	Newcrom A Column 0.5 x 250mm 5um 100A	Newcrom A	5 um	0.5 mm	250 mm	100 A	Column	£1,148.40
NA-10.010.0510	Newcrom A Column 1 x 10mm 5um 100A	Newcrom A	5 um	1.0 mm	10 mm	100 A	Column	£724.00
NA-10.025.0510	Newcrom A Column 1 x 25mm 5um 100A	Newcrom A	5 um	1.0 mm	25 mm	100 A	Column	£798.89
NA-10.050.0510	Newcrom A Column 1 x 50mm 5um 100A	Newcrom A	5 um	1.0 mm	50 mm	100 A	Column	£893.76
NA-10.100.0510	Newcrom A Column 1 x 100mm 5um 100A	Newcrom A	5 um	1.0 mm	100 mm	100 A	Column	£923.72
NA-10.150.0510	Newcrom A Column 1 x 150mm 5um 100A	Newcrom A	5 um	1.0 mm	150 mm	100 A	Column	£938.69
NA-10.250.0510	Newcrom A Column 1 x 250mm 5um 100A	Newcrom A	5 um	1.0 mm	250 mm	100 A	Column	£978.64
NA-100.050.0510	Newcrom A Column 10 x 50mm 5um 100A	Newcrom A	5 um	10.0 mm	50 mm	100 A	Column	£2,314.50
NA-100.100.0510	Newcrom A Column 10 x 100mm 5um 100A	Newcrom A	5 um	10.0 mm	100 mm	100 A	Column	£2,766.44
NA-100.150.0510	Newcrom A Column 10 x 150mm 5um 100A	Newcrom A	5 um	10.0 mm	150 mm	100 A	Column	£3,232.08
NA-100.250.0510	Newcrom A Column 10 x 250mm 5um 100A	Newcrom A	5 um	10.0 mm	250 mm	100 A	Column	£4,231.83

Features

Mixed-mode column with negatively charged acidic ion-pairing groups at the terminal end of long ligand chains (100 Å)
Improved retention of weak basic compounds through a cation-exchange mechanism
Enhanced retention of multi-charged compounds
Separation of acids by an ion-exclusion mechanism
Retention of neutral compounds via a reverse-phase mechanism
Low buffer concentration required to generate efficient ion-exchange
Compatible with typical mobile phases for LC-MS
Newcrom range also includes mixed-mode columns Newcrom AH, Newcrom B, and Newcrom BH
Newcrom RI is a special reversed phase column with low silanol activity
Guard columns connect directly to columns and do not require any additional holders

Specifications

	Newcrom A
Mode	Mixed-Mode
Phase	Negatively charged acidic ion-pairing groups at the terminal end of long ligand chains (100 Å)
Particle Type	Fully Porous
Particle Size	3 µm, 5 µm
Pore Size	100 Å
Temperature Range	0 - 50°C
pH Range	1.5 - 7
Pressure Limit	345 bar

Literature