Shodex ODP2 Series HPLC Columns
The Shodex ODP2 HP series offers polymer–based columns for reversed phase chromatography. The efficiency of ODP2 HP columns is improved over most resin-based columns and is comparable with that of silica-based ODS columns. They don't contain C18 functional groups, the separation comes from the particle itself.
ODP2 HP has a better retention of highly polar substances compared to most general purpose silica-based C18 columns. Silica-based C18 ODS columns are susceptible to protein adsorption, resulting in degradation of the column. ODP2 HP is designed to exclude protein and thus, ODP2 HP can be used for analysis of drugs in biological samples containing protein without rapid column deterioration. As ODP2 HP can be used with low salt concentration without loss of peak shapes, it is excellent for LC/MS analysis.
- Provides a large theoretical plate number nearly twice as much as generally available polymer-based reversed phase columns do
- Offers enhanced retention of high polar substances compared to ODS columns
- Suitable for the analysis of small molecules such as pharmaceuticals in the presence of protein matrix
- Ideal for LC/MS analysis of high polar compounds
- Fulfills USP L39 requirements
- The material is completely silanol-free and therefore proteins are not adsorbed in the column
