Agilent ZORBAX Extend-C18 HPLC Columns

Zorbax Extend-C18 HPLC Columns from Agilent

Extend-C18 columns incorporate a unique patented bidentate silane, combined with a double-endcapping process that protects the silica from dissolution at high pH - up to pH 11.5. Columns are best applied for separations of compounds that are either (1) basic and have little or no retention at low or intermediate pHs, (2) more stable or more soluble at high pH, or (3) basic and show poor peak shape at low or intermediate pH.

Agilent ZORBAX Extend-C18 HPLC columns offer high efficiency and selectivity advantages for basic compounds using high pH mobile phases up to pH 11.5. The Extend-C18 columns use a novel bidentate C18-C18 bonding technology combined with a double endcapping process to protect the silica from dissolution at high pH. This results in highly efficient separations with superior peak shape and improved resolution. Based on traditional, fully porous particles available in 1.8 µm, 3.5 µm, and 5 µm sizes for UHPLC and HPLC methods.

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Part Number	Short Description	Phase Type	Phase	USP	Particle Size	ID	Length	Pore Size	Type	Price
764953-902	ZORBAX Extend C18 4.6 x 100mm 3.5um Column	C18	ZORBAX Extend-C18	L1	3.5 um	4.6 mm	100 mm	80 A	Column	£604.00
763600-902	ZORBAX Extend-C18 1 x 150mm 3.5um Column	C18	ZORBAX Extend-C18	L1	3.5 um	1.0 mm	150 mm	80 A	Column	£619.00
765600-902	ZORBAX Extend-C18 1 x 50mm 3.5 mm Column	C18	ZORBAX Extend-C18	L1	3.5 um	1.0 mm	50 mm	80 A	Column	£460.00
758700-902	ZORBAX Extend-C18 2.1 x 100mm 1.8um 1200 Bar RRHD Column	C18	ZORBAX Extend-C18	L1	1.8 um	2.1 mm	100 mm	80 A	Column	£657.00
728700-902	ZORBAX Extend-C18 2.1 x 100mm 1.8um 600 Bar RRHT Column	C18	ZORBAX Extend-C18	L1	1.8 um	2.1 mm	100 mm	80 A	Column	£642.00
758700-902K	ZORBAX Extend-C18 2.1 x 100mm 1.8um RRHD Method Validation Kit	C18	ZORBAX Extend-C18	L1	1.8 um	2.1 mm	100 mm	80 A	Validation Kit	£1,971.00
761753-902	ZORBAX Extend-C18 2.1 x 100mm 3.5um Column	C18	ZORBAX Extend-C18	L1	3.5 um	2.1 mm	100 mm	80 A	Column	£604.00
821125-930	ZORBAX Extend-C18 2.1 x 12.5mm 5um Guard 4pk	C18	ZORBAX Extend-C18	L1	5 um	2.1 mm	12.5 mm	80 A	Guard	£206.00
759700-902	ZORBAX Extend-C18 2.1 x 150mm 1.8um 1200 Bar RRHD Column	C18	ZORBAX Extend-C18	L1	1.8 um	2.1 mm	150 mm	80 A	Column	£801.00
759700-902K	ZORBAX Extend-C18 2.1 x 150mm 1.8um RRHD Method Validation Kit	C18	ZORBAX Extend-C18	L1	1.8 um	2.1 mm	150 mm	80 A	Validation Kit	£2,402.00
773700-902	ZORBAX Extend-C18 2.1 x 150mm 5um Column	C18	ZORBAX Extend-C18	L1	5 um	2.1 mm	150 mm	80 A	Column	£598.00
726700-902	ZORBAX Extend-C18 2.1 x 20mm 1.8um 600 Bar RRHT Column	C18	ZORBAX Extend-C18	L1	1.8 um	2.1 mm	20 mm	80 A	Column	£334.00
724700-902	ZORBAX Extend-C18 2.1 x 30mm 1.8um 600 Bar RRHT Column	C18	ZORBAX Extend-C18	L1	1.8 um	2.1 mm	30 mm	80 A	Column	£414.00
757700-902	ZORBAX Extend-C18 2.1 x 50mm 1.8um 1200 Bar RRHD Column	C18	ZORBAX Extend-C18	L1	1.8 um	2.1 mm	50 mm	80 A	Column	£636.00
727700-902	ZORBAX Extend-C18 2.1 x 50mm 1.8um 600 Bar RRHT Column	C18	ZORBAX Extend-C18	L1	1.8 um	2.1 mm	50 mm	80 A	Column	£555.00
757700-902K	ZORBAX Extend-C18 2.1 x 50mm 1.8um RRHD Method Validation Kit	C18	ZORBAX Extend-C18	L1	1.8 um	2.1 mm	50 mm	80 A	Validation Kit	£1,891.00
735700-902	ZORBAX Extend-C18 2.1 x 50mm 3.5um Column	C18	ZORBAX Extend-C18	L1	3.5 um	2.1 mm	50 mm	80 A	Column	£472.00
760450-902	ZORBAX Extend-C18 2.1 x 50mm 5um Column	C18	ZORBAX Extend-C18	L1	5 um	2.1 mm	50 mm	80 A	Column	£424.00
821725-907	ZORBAX Extend-C18 2.1mm 1.8um UHPLC Guard 3pk	C18	ZORBAX Extend-C18	L1	1.8 um	2.1 mm	5 mm	80 A	Guard	£465.00
758700-302	ZORBAX Extend-C18 3 x 100mm 1.8um 1200 Bar RRHD Column	C18	ZORBAX Extend-C18	L1	1.8 um	3.0 mm	100 mm	80 A	Column	£657.00
728975-302	ZORBAX Extend-C18 3 x 100mm 1.8um 600 Bar RRHT Column	C18	ZORBAX Extend-C18	L1	1.8 um	3.0 mm	100 mm	80 A	Column	£642.00
758700-302K	ZORBAX Extend-C18 3 x 100mm 1.8um RRHD Method Validation Kit	C18	ZORBAX Extend-C18	L1	1.8 um	3.0 mm	100 mm	80 A	Validation Kit	£1,990.00
764953-302	ZORBAX Extend-C18 3 x 100mm 3.5um Column	C18	ZORBAX Extend-C18	L1	3.5 um	3.0 mm	100 mm	80 A	Column	£604.00
759700-302	ZORBAX Extend-C18 3 x 150mm 1.8um 1200 Bar RRHD Column	C18	ZORBAX Extend-C18	L1	1.8 um	3.0 mm	150 mm	80 A	Column	£801.00
763954-302	ZORBAX Extend-C18 3 x 150mm 3.5um Column	C18	ZORBAX Extend-C18	L1	3.5 um	3.0 mm	150 mm	80 A	Column	£658.00
773450-302	ZORBAX Extend-C18 3 x 150mm 5um Column	C18	ZORBAX Extend-C18	L1	5 um	3.0 mm	150 mm	80 A	Column	£581.00
770450-302	ZORBAX Extend-C18 3 x 250mm 5um Column	C18	ZORBAX Extend-C18	L1	5 um	3.0 mm	250 mm	80 A	Column	£647.00
757700-302	ZORBAX Extend-C18 3 x 50mm 1.8um 1200 Bar RRHD Column	C18	ZORBAX Extend-C18	L1	1.8 um	3.0 mm	50 mm	80 A	Column	£630.00
727975-302	ZORBAX Extend-C18 3 x 50mm 1.8um 600 Bar RRHT Column	C18	ZORBAX Extend-C18	L1	1.8 um	3.0 mm	50 mm	80 A	Column	£555.00
757700-302K	ZORBAX Extend-C18 3 x 50mm 1.8um RRHD Method Validation Kit	C18	ZORBAX Extend-C18	L1	1.8 um	3.0 mm	50 mm	80 A	Validation Kit	£1,909.00
735954-302	ZORBAX Extend-C18 3 x 50mm 3.5um Column	C18	ZORBAX Extend-C18	L1	3.5 um	3.0 mm	50 mm	80 A	Column	£472.00
766953-302	ZORBAX Extend-C18 3 x 75mm 3.5um Column	C18	ZORBAX Extend-C18	L1	3.5 um	3.0 mm	75 mm	80 A	Column	£557.00
823750-937	ZORBAX Extend-C18 3mm 1.8um UHPLC Guard 3pk	C18	ZORBAX Extend-C18	L1	1.8 um	3.0 mm	5 mm	80 A	Guard	£479.00
728975-902	ZORBAX Extend-C18 4.6 x 100mm 1.8um 600 Bar RRHT Column	C18	ZORBAX Extend-C18	L1	1.8 um	4.6 mm	100 mm	80 A	Column	£648.00
728975-902K	ZORBAX Extend-C18 4.6 x 100mm 1.8um Method Validation Kit	C18	ZORBAX Extend-C18	L1	1.8 um	4.6 mm	100 mm	80 A	Validation Kit	£1,945.00
764953-902K	ZORBAX Extend-C18 4.6 x 100mm 3.5um Method Validation Kit	C18	ZORBAX Extend-C18	L1	3.5 um	4.6 mm	100 mm	80 A	Validation Kit	£1,811.00
820950-930	ZORBAX Extend-C18 4.6 x 12.5mm 5um Guard 4pk	C18	ZORBAX Extend-C18	L1	5 um	4.6 mm	12.5 mm	80 A	Guard	£206.00
763953-902	ZORBAX Extend-C18 4.6 x 150mm 3.5um Column	C18	ZORBAX Extend-C18	L1	3.5 um	4.6 mm	150 mm	80 A	Column	£658.00
763953-902K	ZORBAX Extend-C18 4.6 x 150mm 3.5um Method Validation Kit	C18	ZORBAX Extend-C18	L1	3.5 um	4.6 mm	150 mm	80 A	Validation Kit	£1,975.00
773450-902	ZORBAX Extend-C18 4.6 x 150mm 5um Column	C18	ZORBAX Extend-C18	L1	5 um	4.6 mm	150 mm	80 A	Column	£598.00
773450-902K	ZORBAX Extend-C18 4.6 x 150mm 5um Method Validation Kit	C18	ZORBAX Extend-C18	L1	5 um	4.6 mm	150 mm	80 A	Validation Kit	£1,776.00
726975-902	ZORBAX Extend-C18 4.6 x 20mm 1.8um 600 Bar RRHT Column	C18	ZORBAX Extend-C18	L1	1.8 um	4.6 mm	20 mm	80 A	Column	£334.00
770953-902	ZORBAX Extend-C18 4.6 x 250mm 3.5um Column	C18	ZORBAX Extend-C18	L1	3.5 um	4.6 mm	250 mm	80 A	Column	£725.00
770450-902	ZORBAX Extend-C18 4.6 x 250mm 5um Column	C18	ZORBAX Extend-C18	L1	5 um	4.6 mm	250 mm	80 A	Column	£647.00
770450-902K	ZORBAX Extend-C18 4.6 x 250mm 5um Method Validation Kit	C18	ZORBAX Extend-C18	L1	5 um	4.6 mm	250 mm	80 A	Validation Kit	£1,923.00
724975-902	ZORBAX Extend-C18 4.6 x 30mm 1.8um 600 Bar RRHT Column	C18	ZORBAX Extend-C18	L1	1.8 um	4.6 mm	30 mm	80 A	Column	£410.00
722975-902	ZORBAX Extend-C18 4.6 x 50mm 1.8um 400 Bar Column	C18	ZORBAX Extend-C18	L1	1.8 um	4.6 mm	50 mm	80 A	Column	£561.00
727975-902	ZORBAX Extend-C18 4.6 x 50mm 1.8um 600 Bar RRHT Column	C18	ZORBAX Extend-C18	L1	1.8 um	4.6 mm	50 mm	80 A	Column	£555.00
727975-902K	ZORBAX Extend-C18 4.6 x 50mm 1.8um Method Validation Kit	C18	ZORBAX Extend-C18	L1	1.8 um	4.6 mm	50 mm	80 A	Validation Kit	£1,665.00
735953-902	ZORBAX Extend-C18 4.6 x 50mm 3.5um Column	C18	ZORBAX Extend-C18	L1	3.5 um	4.6 mm	50 mm	80 A	Column	£472.00
735953-902K	ZORBAX Extend-C18 4.6 x 50mm 3.5um Method Validation Kit	C18	ZORBAX Extend-C18	L1	3.5 um	4.6 mm	50 mm	80 A	Validation Kit	£1,402.00
746450-902	ZORBAX Extend-C18 4.6 x 50mm 5um Column	C18	ZORBAX Extend-C18	L1	5 um	4.6 mm	50 mm	80 A	Column	£424.00
766953-902	ZORBAX Extend-C18 4.6 x 75mm 3.5um Column	C18	ZORBAX Extend-C18	L1	3.5 um	4.6 mm	75 mm	80 A	Column	£557.00
820750-906	ZORBAX Extend-C18 4.6mm 1.8um UHPLC Guard 3pk	C18	ZORBAX Extend-C18	L1	1.8 um	4.6 mm	5 mm	80 A	Guard	£470.00

Features

Robust performance and long lifetimes under high pH
Unique bidentate bonding and double endcapping provides high pH stability
More efficiency and better peak shape than polymer-based columns
Improve retention, resolution and peak shape of basic compounds
High sensitivity for LC/MS separations using ammonium hydroxide at pH 10.5
Guards extend the lifetime of analytical columns
USP L1 classification
1.8 µm RRHD columns rated to 1200 bar for highest UHPLC performance, and 1.8 µm RRHT columns ultra-fast chromatography rated to 600 bar
3.5 µm columns rated to 400 bar for higher resolution HPLC methods
5 µm columns for proven and reliable HPLC methods
Available in 7 µm for preparative HPLC

Specifications

	ZORBAX Extend-C18
Bonded Phase	C18
Particle Type	Fully Porous
Particle Size	1.8 µm, 3.5 µm, 5 µm, 7 µm
Pore Size	80 Å
Surface Area	180 m²/g
Endcapped	Double
Carbon Load	4%
Maximum Temperature	60°C
pH Range	2 - 11.5
Pressure Limit	1.8 µm RRHT - 600 bar 1.8 µm RRHD - 1200 bar 3.5 µm - 400 bar 5 µm - 400 bar
Hardware	Stainless Steel
USP Designation	L1

Literature

Zorbax Columns Poster (2.76 MB)

A proven and reliable portfolio of totally porous HPLC columns

Zorbax RRHD Column Brochure (2.17 MB)

Achieve true high-definition separations without sacrificing stability

Zorbax Method Validation Kits (786.77 kB)

Validation Kits contain 3 HPLC columns with the same column type but from different manufacturing lots