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Silicycle SiliaPrep C18 SPE

Silicycle SiliaPrep C18 SPE is a strongly hydrophobic and non-polar sorbent for the extraction of a wide range of compounds from different sample matrices. Available in endcapped, non-endcapped and wide pore versions to suit all application types.

SiliaPrep C18 is an innovative endcapped C18 phase characterized by a homogeneous coverage of the silane on the surface. This strongly hydrophobic and non-polar sorbent is used to extract acidic, neutral, and basic compounds from aqueous solutions, various organic compounds from water, and drugs and metabolites from physiological fluids.

SilicPrep C18 nec is a strongly hydrophobic and non-polar non-endcapped C18 sorbent. It is similar to SiliaPrep C18 but has a higher retention and polar selectivity for basic compounds. Unreacted surface OH’s can be used for soft condition catch and release purification of glucuronides.

SiliaPrep C18 WPD is a strongly hydrophobic, non-polar and high loading capacity sorbent which can accommodate larger molecules and untreated matrices due to its larger pore size of 125 Å.

Part Number Short Description Bed Mass SPE Format Tube Size (ml) Phase Type Phase Particle Size Pore Size Material Pack Size Price Qty
96W-R00230B-B SiliaPrep C18 (17%) 96 Well Plate, 50mg/2mL, Silica-Based, 40 - 63um, 60A, 1pk 50 mg 96-Well Plate 2 mL C18 SiliaPrep C18 40 - 63 um 60 A Silica Based 1
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96W-R00230B-C SiliaPrep C18 (17%) 96 Well Plate, 100mg/2mL, Silica-Based, 40 - 63um, 60A, 1pk 100 mg 96-Well Plate 2 mL C18 SiliaPrep C18 40 - 63 um 60 A Silica Based 1
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96W-R33229G-B SiliaPrep C18 WPD 96 Well Plate, 50mg/2mL, Silica-Based, 37 - 55um, 125A, 1pk 50 mg 96-Well Plate 2 mL C18 SiliaPrep C18 WPD 37 - 55 um 125 A Silica Based 1
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96W-R33229G-C SiliaPrep C18 WPD 96 Well Plate, 100mg/2mL, Silica-Based, 37 - 55um, 125A, 1pk 100 mg 96-Well Plate 2 mL C18 SiliaPrep C18 WPD 37 - 55 um 125 A Silica Based 1
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96W-R35530B-B SiliaPrep C18 (17%) nec 96 Well Plate, 50mg/2mL, Silica-Based, 40 - 63um, 60A, 1pk 50 mg 96-Well Plate 2 mL C18 SiliaPrep C18 nec 40 - 63 um 60 A Silica Based 1
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96W-R35530B-C SiliaPrep C18 (17%) nec 96 Well Plate, 100mg/2mL, Silica-Based, 40 - 63um, 60A, 1pk 100 mg 96-Well Plate 2 mL C18 SiliaPrep C18 nec 40 - 63 um 60 A Silica Based 1
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SPE-R00230B-01B SiliaPrep C18 (17%) SPE Cartridges, 50mg/1mL, Silica-Based, 40 - 63um, 60A, 100pk 50 mg Cartridge 1 mL C18 SiliaPrep C18 40 - 63 um 60 A Silica Based 100
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SPE-R00230B-01C SiliaPrep C18 (17%) SPE Cartridges, 100mg/1mL, Silica-Based, 40 - 63um, 60A, 100pk 100 mg Cartridge 1 mL C18 SiliaPrep C18 40 - 63 um 60 A Silica Based 100
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SPE-R00230B-03G SiliaPrep C18 (17%) SPE Cartridges, 200mg/3mL, Silica-Based, 40 - 63um, 60A, 50pk 200 mg Cartridge 3 mL C18 SiliaPrep C18 40 - 63 um 60 A Silica Based 50
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SPE-R00230B-03P SiliaPrep C18 (17%) SPE Cartridges, 500mg/3mL, Silica-Based, 40 - 63um, 60A, 50pk 500 mg Cartridge 3 mL C18 SiliaPrep C18 40 - 63 um 60 A Silica Based 50
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SPE-R00230B-06P SiliaPrep C18 (17%) SPE Cartridges, 500mg/6mL, Silica-Based, 40 - 63um, 60A, 50pk 500 mg Cartridge 6 mL C18 SiliaPrep C18 40 - 63 um 60 A Silica Based 50
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SPE-R00230B-06S SiliaPrep C18 (17%) SPE Cartridges, 1g/6mL, Silica-Based, 40 - 63um, 60A, 50pk 1 g Cartridge 6 mL C18 SiliaPrep C18 40 - 63 um 60 A Silica Based 50
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SPE-R00230B-06U SiliaPrep C18 (17%) SPE Cartridges, 2g/6mL, Silica-Based, 40 - 63um, 60A, 50pk 2 g Cartridge 6 mL C18 SiliaPrep C18 40 - 63 um 60 A Silica Based 50
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SPE-R00230B-12U SiliaPrep C18 (17%) SPE Cartridges, 2g/12mL, Silica-Based, 40 - 63um, 60A, 20pk 2 g Cartridge 12 mL C18 SiliaPrep C18 40 - 63 um 60 A Silica Based 20
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SPE-R33229G-01B SiliaPrep C18 WPD SPE Cartridges, 50mg/1mL, Silica-Based, 37 - 55um, 125A, 100pk 50 mg Cartridge 1 mL C18 SiliaPrep C18 WPD 37 - 55 um 125 A Silica Based 100
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SPE-R33229G-01C SiliaPrep C18 WPD SPE Cartridges, 100mg/1mL, Silica-Based, 37 - 55um, 125A, 100pk 100 mg Cartridge 1 mL C18 SiliaPrep C18 WPD 37 - 55 um 125 A Silica Based 100
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SPE-R33229G-03G SiliaPrep C18 WPD SPE Cartridges, 200mg/3mL, Silica-Based, 37 - 55um, 125A, 50pk 200 mg Cartridge 3 mL C18 SiliaPrep C18 WPD 37 - 55 um 125 A Silica Based 50
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SPE-R33229G-03P SiliaPrep C18 WPD SPE Cartridges, 500mg/3mL, Silica-Based, 37 - 55um, 125A, 50pk 500 mg Cartridge 3 mL C18 SiliaPrep C18 WPD 37 - 55 um 125 A Silica Based 50
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SPE-R33229G-06P SiliaPrep C18 WPD SPE Cartridges, 500mg/6mL, Silica-Based, 37 - 55um, 125A, 50pk 500 mg Cartridge 6 mL C18 SiliaPrep C18 WPD 37 - 55 um 125 A Silica Based 50
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SPE-R33229G-06S SiliaPrep C18 WPD SPE Cartridges, 1g/6mL, Silica-Based, 37 - 55um, 125A, 50pk 1 g Cartridge 6 mL C18 SiliaPrep C18 WPD 37 - 55 um 125 A Silica Based 50
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SPE-R33229G-06U SiliaPrep C18 WPD SPE Cartridges, 2g/6mL, Silica-Based, 37 - 55um, 125A, 50pk 2 g Cartridge 6 mL C18 SiliaPrep C18 WPD 37 - 55 um 125 A Silica Based 50
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SPE-R33229G-12U SiliaPrep C18 WPD SPE Cartridges, 2g/12mL, Silica-Based, 37 - 55um, 125A, 20pk 2 g Cartridge 12 mL C18 SiliaPrep C18 WPD 37 - 55 um 125 A Silica Based 20
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SPE-R35530B-01B SiliaPrep C18 (17%) nec SPE Cartridges, 50mg/1mL, Silica-Based, 40 - 63um, 60A, 100pk 50 mg Cartridge 1 mL C18 SiliaPrep C18 nec 40 - 63 um 60 A Silica Based 100
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SPE-R35530B-01C SiliaPrep C18 (17%) nec SPE Cartridges, 100mg/1mL, Silica-Based, 40 - 63um, 60A, 100pk 100 mg Cartridge 1 mL C18 SiliaPrep C18 nec 40 - 63 um 60 A Silica Based 100
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SPE-R35530B-03G SiliaPrep C18 (17%) nec SPE Cartridges, 200mg/3mL, Silica-Based, 40 - 63um, 60A, 50pk 200 mg Cartridge 3 mL C18 SiliaPrep C18 nec 40 - 63 um 60 A Silica Based 50
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SPE-R35530B-03P SiliaPrep C18 (17%) nec SPE Cartridges, 500mg/3mL, Silica-Based, 40 - 63um, 60A, 50pk 500 mg Cartridge 3 mL C18 SiliaPrep C18 nec 40 - 63 um 60 A Silica Based 50
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SPE-R35530B-06P SiliaPrep C18 (17%) nec SPE Cartridges, 500mg/6mL, Silica-Based, 40 - 63um, 60A, 50pk 500 mg Cartridge 6 mL C18 SiliaPrep C18 nec 40 - 63 um 60 A Silica Based 50
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SPE-R35530B-06S SiliaPrep C18 (17%) nec SPE Cartridges, 1g/6mL, Silica-Based, 40 - 63um, 60A, 50pk 1 g Cartridge 6 mL C18 SiliaPrep C18 nec 40 - 63 um 60 A Silica Based 50
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SPE-R35530B-06U SiliaPrep C18 (17%) nec SPE Cartridges, 2g/6mL, Silica-Based, 40 - 63um, 60A, 50pk 2 g Cartridge 6 mL C18 SiliaPrep C18 nec 40 - 63 um 60 A Silica Based 50
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SPE-R35530B-12U SiliaPrep C18 (17%) nec SPE Cartridges, 2g/12mL, Silica-Based, 40 - 63um, 60A, 20pk 2 g Cartridge 12 mL C18 SiliaPrep C18 nec 40 - 63 um 60 A Silica Based 20
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  • SiliaPrep C18 is a silica based C18 sorbent available in endcapped, non-endcapped and wide pore formats
  • Excellent separation due to narrow particle size distribution and no fines
  • High recovery and yield
  • Reproducible flow rates from lot-to-lot
  • Available in different formats including SPE cartridges and 96 well plates
  • Standard SiliaPrep cartridges are made with flanged polypropylene (PP) tubes and 20 μm polyethylene (PE) frits
  • Larger sizes are also available under SiliaSep OT branding
  SiliaPrep C18 SiliaPrep C18 nec SiliaPrep C18 WPD
Support Backbone Silica Gel Silica Gel Silica Gel
Phase C18 C18 C18
Endcapping Endcapped Non-endcapped Endcapped
Particle Shape Irregular Irregular Irregular
Particle Size 40 - 63 µm 40 - 63 µm 37 - 55 µm
Pore Size 60 Å 60 Å 125 Å
SiliaPrep Brochure (1.19 MB)
Silica based SPE cartridges and well plates from Silicycle
Silicycle Sample Prep Brochure (6.36 MB)
Solutions for sample preparation from Silicycle
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