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Thermo Scientific MAbPac SCX-10 Columns

Thermo Scientific MAbPac SCX-10 columns are designed specifically for high-resolution, high efficiency separation of monoclonal antibodies and their variants. The non-porous pellicular resin provides high resolution, permitting the separation of monoclonal antibody variants that differ by as little as one charge. A hydrophilic layer surrounds the polymeric beads and eliminates hydrophobic interactions with the resin, resulting in very efficient peaks. A proprietary grafted cation-exchange surface provides pH selectivity control for high-resolution separations.

The MAbPac SCX-10 columns are available in several particle sizes. 10 µm particle size columns are available in PEEK while 5 µm columns are available in both PEEK and PEEK-lined stainless steel housings for UHPLC based rapid separation (RS) applications. The MAbPac SCX-10 5 µm shorter columns are recommended for fast separations and are ideal for high throughput needs. Longer columns provide greater resolution.

The MAbPac SCX-10RS columns are packed in PEEK-lined stainless steel columns for UHPLC operating compatibility. High flow rates can be used to achieve faster mAb analysis. These RS columns are suitable for operation up to 7000 psi. The RS bioinert column bodies prevent metal interferences which can result in comprimsed mAb separations. The RS columns are designed for use with bioinert UHPLC systems.

Part Number Short Description Phase Particle Size ID Length Pore Size Type Price Qty
085209 MAbPac SCX-10 RS, 5um, 4.6 x 150mm, Column MAbPac SCX-10 5 um 4.6 mm 150 mm Non-porous Column
£1,763.59
088242 MAbPac SCX-10 RS, 5um, 2.1 x 150mm, Column MAbPac SCX-10 5 um 2.1 mm 150 mm Non-porous Column
£1,764.77
088783 MAbPac SCX-10, 10um, 4 x 250mm, 3 Column Set (3 Lots of Resin) MAbPac SCX-10 10 um 4.0 mm 250 mm Non-porous Column
£2,829.73
088784 MAbPac SCX-10, 10um, 9 x 250mm, Column MAbPac SCX-10 10 um 9.0 mm 250 mm Non-porous Column
£2,341.28
074625 MAbPac SCX-10, 10um, 4 x 250mm, Column MAbPac SCX-10 10 um 4.0 mm 250 mm Non-porous Column
£959.29
074631 MAbPac SCX-10, 10um, 4 x 50mm, Guard Column MAbPac SCX-10 10 um 4.0 mm 50 mm Non-porous Guard
£312.32
075602 MAbPac SCX-10, 10um, 4 x 150mm, Column MAbPac SCX-10 10 um 4.0 mm 150 mm Non-porous Column
£851.27
075603 MAbPac SCX-10, 10um, 4 x 50mm, Column MAbPac SCX-10 10 um 4.0 mm 50 mm Non-porous Column
£743.24
075604 MAbPac SCX-10, 10um, 2 x 250mm, Column MAbPac SCX-10 10 um 2.0 mm 250 mm Non-porous Column
£959.29
075749 MAbPac SCX-10, 10um, 2 x 50mm, Guard Column MAbPac SCX-10 10 um 2.0 mm 50 mm Non-porous Guard
£329.92
078655 MAbPac SCX-10, 5um 4 x 250mm, Column MAbPac SCX-10 5 um 4.0 mm 250 mm Non-porous Column
£1,579.25
078656 MAbPac SCX-10, 5um, 4 x 50mm, Column MAbPac SCX-10 5 um 4.0 mm 50 mm Non-porous Column
£722.11
082515 MAbPac SCX-10 RS, 5um, 2.1 x 250mm Column MAbPac SCX-10 5 um 2.1 mm 250 mm Non-porous Column
£1,960.85
082673 MAbPac SCX-10 RS, 5um, 4.6 x 250mm, Column MAbPac SCX-10 5 um 4.6 mm 250 mm Non-porous Column
£1,960.85
082674 MAbPac SCX-10 RS, 5um, 4.6 x 50mm, Column MAbPac SCX-10 5 um 4.6 mm 50 mm Non-porous Column
£1,470.05
082675 MAbPac SCX-10 RS, 5um, 2.1 x 50mm, Column MAbPac SCX-10 5 um 2.1 mm 50 mm Non-porous Column
£1,470.05
085198 MAbPac SCX-10, 5um, 4 x 150mm, Column MAbPac SCX-10 5 um 4.0 mm 150 mm Non-porous Column
£1,175.34
SP6947 MAbPac SCX-10, 10um, 22 x 250mm, Column MAbPac SCX-10 10 um 22 mm 250 mm Non-porous Column
£15,037.56
  • Exceptionally high resolution for mAb variants
  • Ideal for characterization and quality control assessment of mAbs
  • Well-suited for stability studies, mAb therapeutic method development and high-throughput screening
  • Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing
  • Meets the regulatory requirements for biopharmaceutical characterization
  • MAbPac SCX-10RS has specially developed bio-inert PEEK lined stainless steel column hardware
  • MAbPac SCX-10RS recommended for high throughput analysis using UHPLC
  • Provides complementary selectivity to ProPac WCX-10 for various mAb separations
  MAbPac SCX-10 MAbPac SCX-10RS
Phase Strong Cation Exchange Strong Cation Exchange
Particle Type Polymeric Polymeric
Particle Size 5 µm and 10 µm 5 µm
Pore Size Non-porous Non-porous
pH Range 2 - 12 2 - 12
Maximum Temperature 60°C 60°C
Hardware PEEK PEEK-Lined Stainless Steel
Pressure Limit 10 μm: 3000 psi
5 μm: 5000 psi    
7000 psi
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