YMC BioPro SmartSep Columns

BioPro IEX Media and Preparative Columns from YMC

Ion exchange chromatography (IEX) is widely used in the analysis and purification of bio-molecules. Using reversible charge-charge interactions offers several advantages in comparison to other chromatographic methods, e.g. high capacity and fast throughput. For these reasons, IEX is often used in the capture or intermediate purification of bio-molecules.

BioPro is a series of ion exchange resins specifically designed for use in bio-chromatography. The media is based on a hydrophilic polymer matrix, with particle sizes of 10, 20, 30, or 75 µm. It is available as a strong anion exchanger (BioPro QA) or a strong cation exchanger (BioPro SP). BioPro offers a high dynamic binding capacity (DBC), together with low non-specific adsorption and excellent recovery.

The BioPro Ion Exchange Screening Kits consist of columns that are packed with resins designed for the separation of proteins, nucleotides, and other biomolecules. The available phases are strong anion exchanger (BioPro SmartSep Q), strong cation exchanger (BioPro SmartSep S), weak anion exchanger (BioPro DA) and weak cation exchanger (BioPro CM).

BioPro IEX and BioPro IEX SmartSep from YMC form a series of ion exchange resins specifically designed for biochromatography. It is available as a strong anion exchanger (BioPro IEX Q) and a strong cation exchanger (BioPro IEX S). The media is based on a hydrophilic polymer matrix, with a particle size of 10 µm, 20 µm, 30 µm, and 75 µm. BioPro IEX resins with a 75 µm particle size are especially suited for the initial capture step while the BioPro IEX SmartSep 10 µm, 20 µm, and 30 µm, are the ideal choices for the intermediate purification and polishing processes. BioPro IEX is manufactured in lot sizes up to 450 L.