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YMC Guard Cartridge Holders and Column Couplers

Guard Cartridge Holders from YMC Europe GMBH

YMC offers various different guard cartridge holder concepts for UHPLC, analytical and semi-prep.

    YMC offer a UHPLC guard cartridge holder (XPCHUHP for 5 mm cartridges). The UHPLC holder has a zero-dead-volume direct connection to column to minimize the impact on separation. The guard cartridge holder is stable at high pressures up to 1000 bar (15,000 psi).

      The universal finger tight system is for all column internal diameters from 1 to 4.6 mm id (XPGCH-Q1 for 10 mm cartridges and XPGCH-Q2 for 20 mm cartridges). This system guarantees a low dead volume connection between the guard cartridge and the main column irrespective of the type of column fitting used. The guard cartridge holder gives leak-proof connection to the analytical column up to 420 bar (6,000 psi).

        YMC offers a specific integral guard cartridge holder (XPGCS-Q1 for 10 mm and XPGCS-Q2 for 20 mm length cartridges with 1, 2.1 3 or 4 mm inner diameters). This holder is screwed directly on the YMC cartridge column system in place of the removable end fitting (part numbers ending in QT). The guard cartridges are inserted in the holder cavity without the need to use any tools. These integral guard cartridge holders will not attach to columns with part numbers ending in WT or PT.

          For semi-prep columns several guard holders are available. As the holder for these cartridges feature Parker-compatible fittings (port depth 0.09 inch). It is essential that slip-free fittings are used or specially made stainless steel fittings with stainless steel capillaries are made up so that differences between Valco-compatible (port depth 0.08 inch), Parker-compatible (port depth 0.09 inch) and/or Waters-compatible (port depth 0.13 inch) column endfittings can be accommodated. Due to the higher flowrates involved in semi-prep and prep chromatography the use of PEEK capillaries should be avoided if possible. The part number of semiprep guard cartridges ends -CC. The part numbers for the guard cartridge holders are XPCHSPW1 (10 mm i.d.), XPCHSPW2 (20 mm i.d.) or XPCHSPW3 (30 mm i.d.).

YMC guard cartridge holders are used to connect YMC guard cartridges to LC columns to help extend the lifetime of the column. Column couplers are used to connect stand-alone holders to the columns. Various formats are available for UHPLC, analytical and semi-prep guard cartridges.

UHPLC guard cartridges with 1.9 µm particle size are designed to be used with the UHPLC holder. Designed to connect directly to the UHPLC column to reduce extra column effects while meeting the demands of extreme pressure up to 1400 bar.

For analytical guard cartidges with internal diameters of 1.0 – 4.6 mm there are two guard cartridge holders available depending on which length guard cartridge is used. The holder for the 10 mm length cartridges consists of a holder and connector. For 20 mm length cartridges, the holder is combined with a MarvelX universal connector. Both systems guarantee a low dead volume connection between the guard cartridge and the main column.

Semi-prep guard cartridges come in 10 x 10 mm ID, 10 x 20 mm ID, and 10 x 30 mm ID sizes, with separate holders available for each internal diameter. The constructed guard and holder can be attached to the main column with a column coupler.

Part Number Short Description Type Price Qty
XRCP1601E-1PK Capillary Column Coupler 1/16in OD, 0.1mm ID, 10-32 Coupler
XRCP3201E-1PK Capillary Column Coupler 1/32in OD, 0.13mm ID, 6-40 Coupler
XRCP1602 Column Coupler 1/16in OD, 0.25mm ID for <10mm ID Columns Coupler
XRCP1605 Column Coupler 1/16in OD, 0.5mm ID for 10mm ID Columns Coupler
XRCP1620 Column Coupler 1/16in OD, 0.8mm ID for 50mm ID Columns Coupler
XPCHSPW1 External Guard Cartridge Holder for 10mm ID Guard Cartridges Guard Holder
XPGHFSP20ID External Guard Cartridge Holder for 20mm ID Guard Cartridges Guard Holder
XPGHFSP30ID External Guard Cartridge Holder for 30mm ID Guard Cartridges Guard Holder
XPGCH-Q1 External Guard Cartridge Holder for 1 - 4.6mm ID x 10mm Length Guard Cartridges Guard Holder
XRHTF-01 Hand-tight EXP Fitting with 1 Titanium Ferrule Coupler
XRP0204 Handy Connector 2 for Tubing System of 1/16in OD (420 bar) Coupler
XRHTF-05 Replacement Titanium Hybrid Ferrule for XPCHUHP, 5pk Ferrule
XPCHUHP UHPLC Guard Cartridge Holder for 5mm Guard Cartridge Guard Holder
XPGCH-Q2E External Guard Cartridge Holder for 2.1 - 4mm ID x 20mm Length Guard Cartridges with MarvelX Coupler Guard Holder
  • All YMC guard cartridges require to be used with a guard holder
  • Holders available for UHPLC guard cartridges, standard HPLC guard cartridges, and semi-prep guard cartridges
  • Separate holders available for 10 mm and 20 mm analytical guard cartridges
  • Choose the holder based on the internal diameter of the guard cartridges
  • Column couplers are used to connect stand alone guard holders to the main column   
YMC Column Hardware and Phases Overview (4.14 MB)
Review of the different types of column hardware and phases provided by YMC
YMC UHPLC Guard Cartridge Holder Instructions (348.15 kB)
Best practice for using the YMC UHPLC guards and holder
YMC Analytical HPLC Guard Holder Instructions (378.71 kB)
Guide to using the YMC analytical guard cartridges and holder
YMC Semi-Prep Guard Cartridge Instructions (834.78 kB)
How to install the YMC semi-prep guard cartridges
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