Thermo Scientific ProPac Elite WCX Columns
The Thermo Scientific ProPac Elite WCX column is a weak cation exchange (WCX) column designed for protein characterization including therapeutics such as monoclonal antibodies (mAbs). WCX chromatography is primarily used for the separation and quantitation of mAb and other protein charge variants that can arise during cellular production, downstream purification, storage, and shipping. This unique column chemistry provides excellent performance under a broad range of pH, temperature and mobile phase compositions with excellent recovery and low carryover.
- Superior resolution power for proteins, monoclonal antibodies, and associated charge variants
- High efficiency with reproducible separations
- High recovery with low carry-over
- Wide pH operating range of 2 – 12
- High temperature stability up to 60°C
- High throughput
- Compatible with CX-1 pH Gradient Buffers
| ProPac Elite WCX | |
| Phase | Weak Cation Exchange |
| Particle Type | DVB particles with hydrophilic coating |
| Particle Size | 5 µm |
| Pore Size | Non-porous |
| pH Range | 2 - 12 |
| Maximum Temperature | 60°C |
| Hardware | PEEK |
| Pressure Limit | 310 bar |