Size Exclusion Chromatography (SEC) Columns
Size exclusion chromatography (SEC) columns are the ideal choice for monitoring aggregates of monoclonal antibodies. SEC is a routine technique for the analysis of proteins, and SEC columns are often used to evaluate the aggregation profile of a protein. Protein aggregates are a product of degradation and must be closely monitored and kept within acceptable limits. This is a Critical Quality Attribute (QCA) for monoclonal antibodies (mAbs) and other antibodies because it can cause an immunogenic response in patients.
Browse our range of SEC columns from leading manufacturers in a wide variety of pore sizes to address every aggregate or fragment analysis challenge.