Thermo Scientific Acclaim Mixed-Mode WCX-1 HPLC Columns
Thermo Scientific Acclaim Mixed-Mode WCX-1 HPLC columns provide powerful adjustable selectivity control for the separation of cationic molecules. The silica-based stationary phase features a hydrophobic alkyl chain with a carboxyl terminus that provides both hydrophobic reversed-phase and weak cation-exchange properties. This multimode separation mechanism delivers simultaneous separation of basic and neutral compounds. By independently or simultaneously tuning the mobile phase ionic strength, pH, and organic modifier, you can control the selectivity of ionizable and neutral compounds.
- Multimode retention mechanism: reversed-phase, weak cation-exchange, anion-exclusion, and HILIC modes
- Selectivity complementary to C18 reversed-phase columns
- Powerful selectivity for the separation of difficult mixtures of hydrophobic acids and neutral and cationic analytes
- Efficient primary column for a variety of basic analytes; also, an ideal column for secondary methods development
- Versatile in applications that require different selectivities
- Symmetrical peak shapes and excellent efficiency
- Stable between pH 2.5 and 7.5
- Available in 3 µm and 5μm particle sizes with an average pore diameter of 120 Å
- USP classification of L85
- Range also includes Acclaim Mixed-Mode WAX-1 (reversed phase and weak anion exchange) and Acclaim Mixed-Mode HILIC-1 (reversed phase and HILIC)
| Acclaim Mixed-Mode WCX-1 | |
| Mode | Mixed-Mode |
| Phase Type | Hydrophobic alkyl chain with a carboxyl terminus |
| Particle Type | Fully Porous |
| Particle Size | 3 µm, 5 µm |
| Pore Size | 120 Å |
| Surface Area | 300 m2/g |
| Temperature Limit | 50°C |
| pH Limit | 2.5 - 7.5 |
| Pressure Limit | 400 bar |
| USP Designation | L85 |
Analytical UHPLC and HPLC Columns Brochure
(11.02 MB)
Introduction to the broad range of chemistries and column families from Thermo Scientific
Acclaim Mixed-Mode WCX-1 Product Manual
(473.85 kB)
User guide for the Acclaim Mixed-Mode WCX-1 columns