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Fundamental ICP-MS Training Course

1 Day

An introduction to the fundamental concepts and principles associated with ICP-MS

Attendees will gain useful insight into the operating principles of ICP-MS instruments.

This comprehensive, one-day course is designed to increase expertise and optimise results for all users of ICP-MS.

Understanding sample introduction and the optimisation of instrument performance are key subjects within this one-day course. Interactive training sessions and tutorial exercises are used to reinforce key learning points.

  • How the ICP source differs to other MS techniques, offering a complementary view of the chemicals being analysed
  • Why ICP-MS is particularly suitable for a wide range of applications including isotope ratio studies.
  • How ICP-MS can be used for the analysis of ultra-trace metal elements (0.0005-100ppb)
  • Application of ICP-MS to non-metallic elements (e.g. S, P)


Introduction to IPC-MS

  • What can ICP-MS do?
  • Schematic design

Inductively Coupled Plasmas 

  • Plasma formation
  • Generators
  • Load coils
  • Torches
  • Plasma configuration

Liquid Sample Introduction

  • The cross-flow nebuliser
  • The concentric nebuliser
  • The Babington nebuliser
  • Spray chambers

The Mass Spectrometer

  • The vacuum and interface systems
  • Ion lenses
  • Photon stops
  • Off-Axis deflection
  • Space Charge effect

Mass Analysers

  • Quadrupole theory
  • Alternative Analysers
  • Tuning and calibration/Plasma parameters
  • Continuous Dynode Electron Multiplier

Interferences and Removal

  • Polyatomic and Isobaric interferences
  • Double Charge and Oxide species
  • Plasma / Matrix effects

Analysis Types

  • Collision / Reaction Cells
  • Kinetic Energy Discrimination
  • External / Internal Standards
  • Isotope Dilution
  • Standard Addition

This course is tailored towards either the experienced user who is looking for a refresher course or new users who are looking for an introduction to the analytical technique.

Background knowledge of ICP-OES or mass spectrometry may be useful but not necessary, as all the essentials are covered in the course. Previous experience using ICP-MS equipment can be beneficial.

HPLC Operator

HPLC Troubleshooting

HPLC Method Development

Calibration and Quantitation

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