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HPLC Troubleshooting

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We regularly get enquiries about problems in the lab that require troubleshooting. It can be really frustrating when trying to complete analyses and your instruments just won’t let you. That’s why we made note of the most common problems our customers encountered and turned them into helpful, technical articles.

Take a look and find some tips that will help you get your instruments back online and avoid extended downtime.

  1. Solving Practical HPLC Problems with Basic Theory

    Back to School – Solving Practical HPLC Problems with Basic Theory

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  2. Reducing non-specific protein binding in HPLC

    Reducing non-specific protein binding in HPLC

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  3. HPLC Diagnostic Skills III – Systematic Investigation of Selectivity Changes

    HPLC Diagnostic Skills III – Systematic Investigation of Selectivity Changes

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  4. HPLC Diagnostic Skills II - Tailing Peaks

    HPLC Diagnostic Skills II - Tailing Peaks

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  5. HPLC Troubleshooting Filtration

    HPLC Troubleshooting Filtration

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  6. HPLC Troubleshooting

    HPLC Troubleshooting

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  7. Reduce Instrument Downtime

    Reduce Instrument Downtime

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  8. HPLC Diagnostic Skills Vol I – Noisy Baselines

    HPLC Diagnostic Skills Vol I – Noisy Baselines

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  9. Troubleshooting HPLC Separation Issues - Are checklists only for pilots?

    Troubleshooting HPLC Separation Issues - Are checklists only for pilots?

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  10. Retention Time Variability in HPLC

    Retention Time Variability in HPLC

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  11. Polar analyte retention and phase collapse

    Polar analyte retention and phase collapse

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  12. Solid Phase Extraction Mistakes

    Solid Phase Extraction Mistakes

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